Transcription Factor

Accessions: UP00503A (UniPROBE 20160601)
Names: Abd B, Abd-B, Abd0B, abdB, AbdB-I, AbdB-II, AbdB(CA)[[26]], Abdominal B, AdbB, bex, BX-C, CG10291, CG11648, DmAbdB, Dmel\CG11648, Droabdb, FAB, Fab-7, Fab-8, Fab7, Homeobox protein abdominal-B, iab, IAB 5, iab-5, iab-6, iab-7, iab-8, iab5, iab6, iab7, iab8, iab8.9, iab9, Infraabdominal 7, l(3)89Ed, Mc, Mcp, P3, pH189, Sab, Tab, tuh-3, twig, Uab-5[Sab]
Organisms: Drosophila melanogaster
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: Abdominal B: The Abdominal-B gene, a member of the Drosophila bithorax complex, is required during development to specify the identity of parasegments 10-14.
Length: 83
Pfam Domains: 16-72 Homeobox domain
Sequence:
(in bold interface residues)
1 TPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVK 60
61 IWFQNRRMKNKKNSQRQANQQNN
Interface Residues: 16, 17, 18, 19, 20, 56, 57, 58, 60, 61, 64, 65, 68, 69, 72
3D-footprint Homologues: 1ig7_A, 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 1zq3_P, 2lkx_A, 3d1n_M, 1nk2_P, 2ld5_A, 7q3o_C, 6es3_K, 1b72_A, 3l1p_A, 3a01_E, 5jlw_D, 3lnq_A, 1jgg_B, 4xrs_G, 2hdd_A, 6m3d_C, 3rkq_B, 2r5y_A, 1puf_B, 1au7_A, 2hos_A, 7psx_B, 5zjt_E, 4cyc_A, 6cqi_A, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 6fqp_B, 5hod_A, 1o4x_A, 4qtr_D, 1le8_B, 6fqq_E, 1du0_A, 1mnm_C, 8g87_X, 1k61_B, 5flv_I, 8him_B
Binding Motifs: UP00503A_1 ggrarrgGymATWAAattyhba
Binding Sites: TAATAAAA
GGTAATTA
ATTAATTA
ATTTTATG
CAATAAAA
CCATAAAA
CCCATAAA
GCAATAAA
GCCATAAA
GTAATAAA
GTAATTAA
GTAATTAC
GTCATAAA
GTCATTAA
GTCGTAAA
TAATTAAA
TCATAAAA
ACATAAAA
CCATTAAA
GCTATAAA
Publications: Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.