Transcription Factor
| Accessions: | retn (DrosophilaTF 1.1), T007795_1.02 (CISBP 1.02) |
| Names: | DRI_DROME, Protein dead ringer, Protein retained, retn, T007795_1.02; |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, CISBP 1.02 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Uniprot: | Q24573 |
| Notes: | experiment type:PBM, family:ARID/BRIGHT |
| Length: | 911 |
| Pfam Domains: | 292-381 ARID/BRIGHT DNA binding domain |
| Sequence: (in bold interface residues) | 1 MQLRVHPTMDCSGRSTSNIERDSDLGDDLSHGDRTDDEMRDCDSVDGEHHQLSAKAAIAA 60 61 RLSHTVSGGGGSFASPEPQTELPLSHHHQLPPNHPLNALGSFMGIGGLHSIPNLQHSDVL 120 121 EKLKMQVRDMKVGLMEQDYAAAAHAAAFGANMLPTTISSGFPLPHNSVAFGHVTSSPSGG 180 181 NGSSYNGGTTPTNSSNSNATTNGGGTAGPGGTGGSGGGGGGGGGGGGGVGGHQFSFASPT 240 241 AAPSGKEARHFAANSASNSSTSSEASNSSQQNNGWSFEEQFKQVRQLYEINDDPKRKEFL 300 301 DDLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEIIKGLHLPS 360 361 SITSAAFTLRTQYMKYLYPYECEKKNLSTPAELQAAIDGNRREGRRSSYGQYEAMHNQMP 420 421 MTPISRPSLPGGMQQMSPLALVTHAAVANNQQAQAAAAAAAAHHRLMGAPAFGQMPNLVK 480 481 QEIESRMMEYLQLIQAKKEQGMPPVLGGNHPHQQQHSQQQQQQQHHHQQQQQQQSQQQHH 540 541 LQQQRQRSQSPDLSKHEALSAQVALWHMYHNNNSPPGSAHTSPQQREALNLSDSPPNLTN 600 601 IKREREREPTPEPVDQDDKFVDQPPPAKRVGSGLLPPGFPANFYLNPHNMAAVAAAAGFH 660 661 HPSMGHQQDAASEGEPEDDYAHGEHNTTGNSSSMHDDSEPQQMNGHHHHQTHHLDKSDDS 720 721 AIENSPTTSTTTGGSVGHRHSSPVSTKKKGGAKPQSGGKDVPTEDKDASSSGKLNPLETL 780 781 SLLSGMQFQVARNGTGDNGEPQLIVNLELNGVKYSGVLVANVPLSQSETRTSSPCHAEAP 840 841 TVEEEKDEEEEEEPKAAEEESHRSPVKQENEDVDQDMEGSEVLLNGGASAVGGAGAGVGV 900 901 GVPLLKDAVVS |
| Interface Residues: | 350, 363, 364, 367, 368, 402, 509, 512, 513, 516, 517, 522, 524 |
| 3D-footprint Homologues: | 2oeh_A, 1kqq_A, 2wt7_B, 2lkx_A |
| Binding Motifs: | retn tyrATTAatm M0111_1.02 tttrATwr |
| Publications: | Gregory S. L., Kortschak R. D., Kalionis B., Staint R. Characterization of the dead ringer gene identifies a novel, highly conserved family of sequence-specific DNA-binding proteins. Mol. Cell. Biol. 16:792-799 (1996). [Pubmed] |
| Related annotations: | PaperBLAST |
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