Transcription Factor
| Accessions: | P31276 (JASPAR 2024) |
| Names: | Homeobox protein Hox-3G, Homeobox protein Hox-C13, HXC13_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P31276 |
| Length: | 330 |
| Pfam Domains: | 56-168 Hox protein A13 N terminal 261-317 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGL 60 61 GSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLG 120 121 YGYPFGGSYYGCRLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFAS 180 181 SYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLW 240 241 KSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLS 300 301 ERQVTIWFQNRRVKEKKVVSKSKAPHLHST |
| Interface Residues: | 246, 260, 261, 262, 263, 264, 302, 303, 305, 306, 309, 310, 313, 314, 317 |
| 3D-footprint Homologues: | 1e3o_C, 3a01_E, 6a8r_A, 1puf_A, 1ig7_A, 5zfz_A, 1fjl_B, 3cmy_A, 2h1k_B, 3lnq_A, 1jgg_B, 1nk2_P, 6m3d_C, 1zq3_P, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 1b72_A, 2r5y_A, 5jlw_D, 2hdd_A, 4xrs_G, 1puf_B, 3rkq_B, 5flv_I, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 2xsd_C, 7xrc_C, 1au7_A, 1le8_A, 4qtr_D, 1mnm_C, 1du0_A, 1k61_B, 1o4x_A |
| Binding Motifs: | MA0907.1 gCTCGTAAAAh MA0907.2 CTCGTAAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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