Transcription Factor
| Accessions: | GATA3_HUMAN (HOCOMOCO 10), P23771 (JASPAR 2024) |
| Names: | GATA-binding factor 3, GATA3_HUMAN, Trans-acting T-cell-specific transcription factor GATA-3 |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 443 |
| Pfam Domains: | 263-296 GATA zinc finger 317-349 GATA zinc finger |
| Sequence: (in bold interface residues) | 1 MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFNIDGQGNHV 60 61 PPYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKT 120 121 SIHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDE 180 181 KECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVPEYSSGLFPPSSLL 240 241 GGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPL 300 301 IKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEG 360 361 IQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSSHMLTTPT 420 421 PMHPPSSLSFGPHHPSSMVTAMG |
| Interface Residues: | 107, 108, 272, 273, 275, 285, 289, 326, 327, 329, 339, 343, 344, 347, 364, 366, 367 |
| 3D-footprint Homologues: | 2fr4_L, 4hc9_A, 3vd6_C, 3dfx_B, 1gat_A, 4gat_A |
| Binding Motifs: | MA0037.2 AGATAARa GATA3_HUMAN.H10MO.C|M01175 wsWGATAAraw MA0037.1 wGATwg MA0037.3 wGATAAsr |
| Binding Sites: | MA0037.1.1 MA0037.1.10 MA0037.1.11 MA0037.1.12 / MA0037.1.9 MA0037.1.13 MA0037.1.14 MA0037.1.15 MA0037.1.16 MA0037.1.17 MA0037.1.18 MA0037.1.19 MA0037.1.2 MA0037.1.20 MA0037.1.3 MA0037.1.4 MA0037.1.5 MA0037.1.6 MA0037.1.7 MA0037.1.8 MA0037.2.1 MA0037.2.10 / MA0037.2.11 MA0037.2.12 MA0037.2.13 MA0037.2.14 MA0037.2.15 MA0037.2.16 MA0037.2.17 MA0037.2.18 MA0037.2.19 MA0037.2.2 MA0037.2.20 MA0037.2.3 MA0037.2.4 MA0037.2.5 MA0037.2.6 MA0037.2.7 MA0037.2.8 MA0037.2.9 |
| Publications: | Merika M., Orkin S. H. DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13:3999-4010 (1993). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.