Transcription Factor
| Accessions: | T100220_1.02 (CISBP 1.02), G5EEA1 (JASPAR 2024) |
| Names: | lim-4, T100220_1.02;, G5EEA1_CAEEL, LIM domain family, LIM4_CAEEL, Putative transcription factor LIM-4 |
| Organisms: | Caenorhabditis elegans |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Homeodomain |
| Length: | 355 |
| Pfam Domains: | 98-152 LIM domain 168-224 LIM domain 240-296 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MDAHLVQAKKTSTASELSDSSLTFPFIGDYLSSPSLTTSDYVSDCSNLTVEGPVPANQEF 60 61 SSSDESSVYISSALRLADYAFTPDDNIRIKPDAVIVICTQCQHQIQDKFFLSIDGRNYHE 120 121 NCLQCSTCENPLSNKCFYKDKTFYCKGCYFRTHVTSTASSCRELGPKCASCDRTIQATDW 180 181 VRRARNYVYHLACFSCNQCKRQLSTGEEYALQEGNLLCKQHFLELVEGDSGVSSQKAKTK 240 241 RVRTTFAEDQLSVLQTYFNRDSNPDGADLEKIASMTGLSKRVTQVWFQNSRARQKKWHQK 300 301 SEGDNGDSQRSSVGPSSPSQKSDSSSEMMYPTSVTTSVEDAIPDSIVILGSLQFD |
| Interface Residues: | 177, 179, 180, 183, 204, 205, 208, 240, 241, 242, 243, 281, 282, 284, 285, 288, 289, 292, 293, 296, 307, 310 |
| 3D-footprint Homologues: | 7ysf_A, 6a8r_A, 3cmy_A, 2h1k_B, 1ig7_A, 3d1n_M, 5zfz_A, 1fjl_B, 2lkx_A, 1jgg_B, 6m3d_C, 1zq3_P, 3lnq_A, 1nk2_P, 2ld5_A, 1b72_A, 3rkq_B, 4xrs_G, 2hdd_A, 4cyc_A, 2r5y_A, 1puf_B, 5flv_I, 3l1p_A, 2hos_A, 1au7_A, 4j19_B, 3a01_E, 7psx_B, 5hod_A, 5jlw_D, 7q3o_C, 1e3o_C, 1le8_A, 4qtr_D, 1puf_A, 1du0_A, 6es3_K, 5zjt_E |
| Binding Motifs: | M1143_1.02 rsYAATTAr MA0923.1 rsYAATTAr MA0923.2 YAATTAr |
| Publications: | Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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