Transcription Factor

						

			
Accessions: T025983_1.02 (CISBP 1.02), P54841 (JASPAR 2024)

			
Names: Mafb, T025983_1.02;, Kreisler, Maf-B, MAFB_MOUSE, Segmentation protein Kr, Transcription factor Maf-1, Transcription factor MafB, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B
Organisms: Mus musculus
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:bZIP
Length: 323
Pfam Domains:    80-114 Maf N-terminal region
  209-302 bZIP Maf transcription factor
Sequence: 
(in bold interface residues)		   1 MAAELSMGQELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL   60
  61 STPCSSVPSSPSFSPTEPKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQP  120
 121 LQSFDGFRSAHHHHHHHHPHPHHGYPGAGVTHDDLGQHAHPHHHHHHQASPPPSSAASPA  180
 181 QQLPTSHPGPGPHATAAATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLK  240
 241 QKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEK  300
 301 LANSGFREAGSTSDSPSSPEFFL
Interface Residues: 153, 244, 248, 249, 251, 252, 253, 255, 256
3D-footprint Homologues: 7mtl_A, 4eot_A, 7x5e_E, 7x5e_F, 2wt7_B, 5vpe_D, 1dh3_C, 6d6v_A
Binding Motifs: PB0041.1 aawwkTGCTGACwwarm
PB0145.1 maatTGCAaAAwwrt
MA0117.2 awwwTGCTGACd
M0321_1.02 aaatTGCTGACkt
MA0117.3 awwwTGCTGAC
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]


Matsushima-Hibiya Y, Nishi S, Sakai M. Rat maf-related factors: the specificities of DNA binding and heterodimer formation. Biochemical and biophysical research communications 245:412-8 (1998). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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