Transcription Factor
| Accessions: | T098480_1.02 (CISBP 1.02), Q04787 (JASPAR 2024) |
| Names: | bsh, T098480_1.02;, BSH_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q04787 |
| Notes: | experiment type:PBM, family:Homeodomain |
| Length: | 429 |
| Pfam Domains: | 275-331 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MAMLNEASLSPADAHAHANATTPTHSKAAAMASATTMLTTKTPFSIEHILFQNLNSASNN 60 61 NNSSDTNGIAANTNNYAPKSSRNAVKSARSAFAHDNNPHKHPSQHSHPPQSHPPASASAS 120 121 ATATARSNQAASGYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQHPPVP 180 181 TTQPQPPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQA 240 241 SLFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLS 300 301 TPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANEPVDFSRSEPGKQPGEATSS 360 361 SGDSKHGKLNPGSVGGTPTQPTSEQQLQMCLMQQGYSTDDYSDLEADSGDEDNSSDVDIV 420 421 GDAKLYQLT |
| Interface Residues: | 274, 275, 276, 277, 278, 316, 317, 319, 320, 323, 324, 327, 328, 331 |
| 3D-footprint Homologues: | 4j19_B, 1ig7_A, 1puf_A, 5zfz_A, 2h1k_B, 3cmy_A, 1fjl_B, 6a8r_A, 3d1n_M, 1jgg_B, 6m3d_C, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 7q3o_C, 6es3_K, 2ld5_A, 2hos_A, 5jlw_D, 4cyc_A, 2d5v_B, 4xrs_G, 3a01_E, 5flv_I, 5zjt_E, 1au7_A, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 1b72_A, 2xsd_C, 7xrc_C, 1e3o_C, 1le8_A, 1o4x_A, 1le8_B, 1du0_A, 3l1p_A, 1mnm_C, 1puf_B, 8g87_X, 1k61_B, 4qtr_D, 4xrm_B |
| Binding Motifs: | MA0214.1 tTAATkr M1089_1.02 swTAAtkrsy |
| Binding Sites: | MA0214.1.8 MA0214.1.20 / MA0214.1.4 MA0214.1.16 / MA0214.1.17 MA0214.1.18 MA0214.1.1 MA0214.1.10 / MA0214.1.2 MA0214.1.11 MA0214.1.12 / MA0214.1.14 MA0214.1.13 MA0214.1.15 MA0214.1.19 MA0214.1.3 MA0214.1.5 MA0214.1.6 MA0214.1.7 MA0214.1.9 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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