Transcription Factor
| Accessions: | T012482_1.02 (CISBP 1.02), Q9FIP9 (JASPAR 2024) |
| Names: | MYC3, T012482_1.02;, AtbHLH5, Basic helix-loop-helix protein 5, bHLH 5, bHLH transcription factor bHLH005, MYC3_ARATH, Protein ALTERED TRYPTOPHAN REGULATION 2, Transcription factor ATR2, Transcription factor EN 36, Transcription factor MYC3 |
| Organisms: | Arabidopsis thaliana |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9FIP9 |
| Notes: | experiment type:PBM, family:bHLH |
| Length: | 592 |
| Pfam Domains: | 52-235 bHLH-MYC and R2R3-MYB transcription factors N-terminal 415-460 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MNGTTSSINFLTSDDDASAAAMEAFIGTNHHSSLFPPPPQQPPQPQFNEDTLQQRLQALI 60 61 ESAGENWTYAIFWQISHDFDSSTGDNTVILGWGDGYYKGEEDKEKKKNNTNTAEQEHRKR 120 121 VIRELNSLISGGIGVSDESNDEEVTDTEWFFLVSMTQSFVNGVGLPGESFLNSRVIWLSG 180 181 SGALTGSGCERAGQGQIYGLKTMVCIATQNGVVELGSSEVISQSSDLMHKVNNLFNFNNG 240 241 GGNNGVEASSWGFNLNPDQGENDPALWISEPTNTGIESPARVNNGNNSNSNSKSDSHQIS 300 301 KLEKNDISSVENQNRQSSCLVEKDLTFQGGLLKSNETLSFCGNESSKKRTSVSKGSNNDE 360 361 GMLSFSTVVRSAANDSDHSDLEASVVKEAIVVEPPEKKPRKRGRKPANGREEPLNHVEAE 420 421 RQRREKLNQRFYSLRAVVPNVSKMDKASLLGDAISYINELKSKLQQAESDKEEIQKKLDG 480 481 MSKEGNNGKGCGSRAKERKSSNQDSTASSIEMEIDVKIIGWDVMIRVQCGKKDHPGARFM 540 541 EALKELDLEVNHASLSVVNDLMIQQATVKMGSQFFNHDQLKVALMTKVGENY |
| Interface Residues: | 416, 417, 419, 420, 423, 424, 428, 444, 446 |
| 3D-footprint Homologues: | 5nj8_D, 7ssa_L, 5eyo_A, 5v0l_A, 7xi3_A, 5gnj_I, 6g1l_A, 4h10_A, 7xq5_A, 5i50_B, 7d8t_A, 4zpk_A, 8osl_P, 1an4_A, 7z5k_B |
| Binding Motifs: | MA0568.1 vCACGTGb M0165_1.02 cacGTGskww MA0568.2 CACGTG |
| Publications: | Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico J.M, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla J.M, Pauwels L, Witters E, Puga M.I, Paz-Ares J, Goossens A, Reymond P, De Jaeger G, Solano R. The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses. The Plant cell 23:701-15 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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