Transcription Factor

Accessions: Q570R7 (JASPAR 2024), T21780 (AthalianaCistrome v4_May2016)
Names: AtbHLH72, Basic helix-loop-helix protein 72, bHLH 72, bHLH transcription factor bHLH072, Phytochrome-interacting factor 7, PIF7_ARATH, Transcription factor EN 109, Transcription factor PIF7, AT5G61270, PIF7, T21780;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: DAP-seq, family:bHLH
Length: 366
Pfam Domains: 171-216 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MSNYGVKELTWENGQLTVHGLGDEVEPTTSNNPIWTQSLNGCETLESVVHQAALQQPSKF 60
61 QLQSPNGPNHNYESKDGSCSRKRGYPQEMDRWFAVQEESHRVGHSVTASASGTNMSWASF 120
121 ESGRSLKTARTGDRDYFRSGSETQDTEGDEQETRGEAGRSNGRRGRAAAIHNESERRRRD 180
181 RINQRMRTLQKLLPTASKADKVSILDDVIEHLKQLQAQVQFMSLRANLPQQMMIPQLPPP 240
241 QSVLSIQHQQQQQQQQQQQQQQQQQFQMSLLATMARMGMGGGGNGYGGLVPPPPPPPMMV 300
301 PPMGNRDCTNGSSATLSDPYSAFFAQTMNMDLYNKMAAAIYRQQSDQTTKVNIGMPSSSS 360
361 NHEKRD
Interface Residues: 170, 171, 172, 174, 175, 178, 179, 201
3D-footprint Homologues: 1an4_A, 5nj8_D, 4h10_A, 7d8t_A, 5gnj_I, 7xi3_A, 5v0l_A, 7f2f_B, 5i50_B, 1am9_A, 4zpk_A, 7ssa_L, 6g1l_A, 5eyo_A, 4h10_B, 8osl_P, 8osl_O, 7xi3_B, 7z5k_B, 7xhv_B, 5nj8_C, 5v0l_B
Binding Motifs: M0176 / MA1364.1 swkrrwsCCACGTGg
MA1364.2 sCCACGTGg
Publications: Huq E., Al-Sady B., Hudson M., Kim C., Apel K., Quail P. H. Phytochrome-interacting factor 1 is a critical bHLH regulator of chlorophyll biosynthesis.. Science 305:1937-1941 (2004). [Pubmed]
Related annotations: PaperBLAST

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