Transcription Factor

Accessions: CEBPG_HUMAN (HOCOMOCO 10), P53567 (JASPAR 2024)
Names: C/EBP gamma, CCAAT/enhancer-binding protein gamma, CEBPG_HUMAN
Organisms: Homo sapiens
Libraries: HOCOMOCO 10 1, JASPAR 2024 2
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 150
Pfam Domains: 62-114 Basic region leucine zipper
65-120 bZIP transcription factor
Sequence:
(in bold interface residues)
1 MSKISQQNSTPGVNGISVIHTQAHASGLQQVPQLVPAGPGGGGKAVAPSKQSKKSSPMDR 60
61 NSDEYRQRRERNNMAVKKSRLKSKQKAQDTLQRVNQLKEENERLEAKIKLLTKELSVLKD 120
121 LFLEHAHNLADNVQSISTENTTADGDNAGQ
Interface Residues: 68, 69, 72, 73, 75, 76, 79, 80
3D-footprint Homologues: 2wt7_A, 6mg1_B, 1nwq_C, 2c9l_Z
Binding Motifs: MA0838.1 rTTrCGCAAy
CEBPG_HUMAN.H10MO.C|M01052 aTKktGcAATctk
MA1636.1 adATGATGCAATmwt
MA1636.2 ATGATGCAAT
Binding Sites: MA1636.1.1
MA1636.1.10 / MA1636.1.5
MA1636.1.11 / MA1636.1.7
MA1636.1.12
MA1636.1.13 / MA1636.1.8
MA1636.1.14 / MA1636.1.9
MA1636.1.15
MA1636.1.16
MA1636.1.10 / MA1636.1.17
MA1636.1.11 / MA1636.1.18
MA1636.1.19
MA1636.1.2
MA1636.1.12 / MA1636.1.20
MA1636.1.3
MA1636.1.3 / MA1636.1.4
MA1636.1.4 / MA1636.1.5
MA1636.1.6
MA1636.1.7
MA1636.1.8
MA1636.1.9
MA1636.1.13
MA1636.1.14
MA1636.1.15
MA1636.1.16
MA1636.1.17
MA1636.1.18
MA1636.1.19
MA1636.1.20
MA1636.1.6
MA1636.2.9
MA1636.2.1
MA1636.2.13
MA1636.2.16
MA1636.2.17
MA1636.2.14
MA1636.2.3
MA1636.2.10 / MA1636.2.4
MA1636.2.2
MA1636.2.11
MA1636.2.12
MA1636.2.15
MA1636.2.18 / MA1636.2.7
MA1636.2.19
MA1636.2.20
MA1636.2.5
MA1636.2.6
MA1636.2.8
Publications: Osada S, Yamamoto H, Nishihara T, Imagawa M. DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J Biol Chem 271:3891-6 (1996). [Pubmed]

Hong S, Skaist AM, Wheelan SJ, Friedman AD. AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription. J Leukoc Biol 90:643-51 (2011). [Pubmed]
Related annotations: PaperBLAST

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