Transcription Factor
Accessions: | A1YPR0 (JASPAR 2024) |
Names: | Affected by papillomavirus DNA integration in ME180 cells protein 1, APM-1, ZBT7C_HUMAN, Zinc finger and BTB domain-containing protein 36, Zinc finger and BTB domain-containing protein 7C, Zinc finger protein 857C |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | A1YPR0 |
Length: | 619 |
Pfam Domains: | 24-127 BTB/POZ domain 381-402 Zinc-finger double domain 392-414 C2H2-type zinc finger 392-414 Zinc finger, C2H2 type 407-431 Zinc-finger double domain 420-442 C2H2-type zinc finger 434-459 Zinc-finger double domain 448-469 C2H2-type zinc finger 448-469 Zinc finger, C2H2 type |
Sequence: (in bold interface residues) | 1 MANDIDELIGIPFPNHSSEVLCSLNEQRHDGLLCDVLLVVQEQEYRTHRSVLAACSKYFK 60 61 KLFTAGTLASQPYVYEIDFVQPEALAAILEFAYTSTLTITAGNVKHILNAARMLEIQCIV 120 121 NVCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDP 180 181 QDISCHQSPSKTDHLTEKAYSDTPRDFPDSFQAGSPGHLGVIRDFSIESLLRENLYPKAN 240 241 IPDRRPSLSPFAPDFFPHLWPGDFGAFAQLPEQPMDSGPLDLVIKNRKIKEEEKEELPPP 300 301 PPPPFPNDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGGLFPPWPLVEERKLKP 360 361 KASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHTGERPY 420 421 LCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRG 480 481 RKPAAWRAASLLFGPGGPAPDKAAFVMPPALGEVGGHLGGAAVCLPGPSPAKHFLAAPKG 540 541 ALSLQELERQFEETQMKLFGRAQLEAERNAGGLLAFALAENVAAARPYFPLPDPWAAGLA 600 601 GLPGLAGLNHVASMSEANN |
Interface Residues: | 350, 352, 353, 356, 374, 375, 376, 377, 378, 380, 381, 383, 384, 387, 400, 401, 402, 403, 404, 405, 406, 409, 413, 430, 431, 432, 433, 434, 435, 436, 437, 438, 458, 459, 460, 461, 462, 463, 464, 465, 466, 469 |
3D-footprint Homologues: | 6wmi_A, 7y3l_A, 7n5w_A, 6jnm_A, 8cuc_F, 8ssu_A, 6ml4_A, 5v3j_F, 5kkq_D, 5ei9_F, 5k5i_A, 8ssq_A, 7w1m_H, 5und_A, 8h9h_G, 7eyi_G, 2lt7_A, 1tf6_A, 2i13_A, 7y3m_I, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 1hwt_C, 1tf3_A, 4x9j_A, 1llm_D, 6blw_A, 6u9q_A, 5yel_A, 1mey_C, 7txc_E, 5kl3_A, 1g2f_F, 2kmk_A, 2gli_A, 5k5l_F, 6a57_A, 3uk3_C, 8gn3_A, 2wbs_A, 1f2i_J, 2drp_D, 5yj3_D, 4m9v_C |
Binding Motifs: | MA0695.1 rcgACCACCgam MA0695.2 cgACCACC |
Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
Related annotations: | PaperBLAST |
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