Transcription Factor

Accessions: A1YPR0 (JASPAR 2024)
Names: Affected by papillomavirus DNA integration in ME180 cells protein 1, APM-1, ZBT7C_HUMAN, Zinc finger and BTB domain-containing protein 36, Zinc finger and BTB domain-containing protein 7C, Zinc finger protein 857C
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: A1YPR0
Length: 619
Pfam Domains: 24-127 BTB/POZ domain
381-402 Zinc-finger double domain
392-414 C2H2-type zinc finger
392-414 Zinc finger, C2H2 type
407-431 Zinc-finger double domain
420-442 C2H2-type zinc finger
434-459 Zinc-finger double domain
448-469 C2H2-type zinc finger
448-469 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MANDIDELIGIPFPNHSSEVLCSLNEQRHDGLLCDVLLVVQEQEYRTHRSVLAACSKYFK 60
61 KLFTAGTLASQPYVYEIDFVQPEALAAILEFAYTSTLTITAGNVKHILNAARMLEIQCIV 120
121 NVCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDP 180
181 QDISCHQSPSKTDHLTEKAYSDTPRDFPDSFQAGSPGHLGVIRDFSIESLLRENLYPKAN 240
241 IPDRRPSLSPFAPDFFPHLWPGDFGAFAQLPEQPMDSGPLDLVIKNRKIKEEEKEELPPP 300
301 PPPPFPNDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGGLFPPWPLVEERKLKP 360
361 KASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHTGERPY 420
421 LCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRG 480
481 RKPAAWRAASLLFGPGGPAPDKAAFVMPPALGEVGGHLGGAAVCLPGPSPAKHFLAAPKG 540
541 ALSLQELERQFEETQMKLFGRAQLEAERNAGGLLAFALAENVAAARPYFPLPDPWAAGLA 600
601 GLPGLAGLNHVASMSEANN
Interface Residues: 350, 352, 353, 356, 374, 375, 376, 377, 378, 380, 381, 383, 384, 387, 400, 401, 402, 403, 404, 405, 406, 409, 413, 430, 431, 432, 433, 434, 435, 436, 437, 438, 458, 459, 460, 461, 462, 463, 464, 465, 466, 469
3D-footprint Homologues: 6wmi_A, 7y3l_A, 7n5w_A, 6jnm_A, 8cuc_F, 8ssu_A, 6ml4_A, 5v3j_F, 5kkq_D, 5ei9_F, 5k5i_A, 8ssq_A, 7w1m_H, 5und_A, 8h9h_G, 7eyi_G, 2lt7_A, 1tf6_A, 2i13_A, 7y3m_I, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 1hwt_C, 1tf3_A, 4x9j_A, 1llm_D, 6blw_A, 6u9q_A, 5yel_A, 1mey_C, 7txc_E, 5kl3_A, 1g2f_F, 2kmk_A, 2gli_A, 5k5l_F, 6a57_A, 3uk3_C, 8gn3_A, 2wbs_A, 1f2i_J, 2drp_D, 5yj3_D, 4m9v_C
Binding Motifs: MA0695.1 rcgACCACCgam
MA0695.2 cgACCACC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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