Transcription Factor

Accessions: UP00043A (UniPROBE 20160601)
Names: B-cell CLL/lymphoma 6, B-cell CLL/lymphoma 6 member B protein, Bazf, Bcl6-associated zinc finger protein, Bcl6b, member B
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: O88282
Description: B-cell CLL/lymphoma 6, member B: Mus musculus B-cell CLL/lymphoma 6, member B, mRNA
Length: 166
Pfam Domains: 15-38 C2H2-type zinc finger
16-38 Zinc finger, C2H2 type
16-38 C2H2-type zinc finger
30-54 Zinc-finger double domain
44-55 C2H2-type zinc finger
44-66 Zinc finger, C2H2 type
44-64 C2H2-type zinc finger
44-62 Zinc-finger of C2H2 type
58-82 Zinc-finger double domain
71-82 C2H2-type zinc finger
72-94 Zinc finger, C2H2 type
72-94 C2H2-type zinc finger
86-111 Zinc-finger double domain
100-115 C2H2-type zinc finger
100-122 Zinc finger, C2H2 type
100-122 C2H2-type zinc finger
115-138 Zinc-finger double domain
128-150 Zinc-finger of C2H2 type
128-151 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 SSGLELLAPGDEDKPYKCQLCRSAFRYKGNLASHRTVHTGEKPYRCSICGARFNRPANLK 60
61 THSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVR 120
121 IHTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGAATNTKVRYHILGG
Interface Residues: 26, 27, 28, 29, 30, 32, 33, 35, 36, 37, 39, 44, 54, 55, 56, 57, 58, 60, 61, 65, 82, 83, 84, 85, 86, 88, 89, 110, 111, 112, 113, 114, 116, 117, 118, 120, 138, 139, 140, 141, 142, 143, 144, 145, 146
3D-footprint Homologues: 7w1m_H, 7y3l_A, 5v3j_F, 7n5w_A, 8ssq_A, 5und_A, 8ssu_A, 2gli_A, 8gn3_A, 5kkq_D, 6wmi_A, 7eyi_G, 8h9h_G, 7y3m_I, 2i13_A, 5yel_A, 2jpa_A, 1ubd_C, 2kmk_A, 6jnm_A, 8cuc_F, 1tf3_A, 5ei9_F, 1mey_C, 1f2i_J, 5k5i_A, 6ml4_A, 1g2f_F, 6blw_A, 1tf6_A, 6u9q_A, 4x9j_A, 1llm_D, 5kl3_A, 2lt7_A, 6e94_A, 7ysf_A, 2drp_D, 7txc_E, 5yj3_D, 6a57_A, 3uk3_C, 2wbs_A, 4m9v_C
Binding Motifs: UP00043A_1 wcTTTCkAGGAAttys
UP00043A_2 hbscCCgCCCCwhmwm
Binding Sites: ACCCCGCC
ACTAGAAA
ACTTTCTA
AGGGGCGG
ATTTCTAG
CCCACCCC
CCGCCCCA
CCGCCCCG
CCTAGAAA
CCTCGAAA
CTAGAAAG
CTTTCTAA
GCCCACCC
GCTTTCTA
GGCGGGGA
TCCAGGAA
TCCTAGAA
TCGAGGAA
TCTAAGAA
TCTAGGAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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