Transcription Factor
| Accessions: | 3wts_C (3D-footprint 20231221), 3wtt_C (3D-footprint 20231221), 3wtu_C (3D-footprint 20231221), 3wtv_C (3D-footprint 20231221), 3wtw_C (3D-footprint 20231221) |
| Names: | ETS1_HUMAN, p54, Protein C-ets-1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P14921 |
| Length: | 118 |
| Pfam Domains: | 17-98 Ets-domain |
| Sequence: (in bold interface residues) | 1 PVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKR 60 61 KNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK |
| Interface Residues: | 14, 47, 51, 52, 55, 69, 70, 72, 73, 74, 76, 77, 91 |
| 3D-footprint Homologues: | 3zp5_A, 2wbs_A, 2stt_A, 8ee9_F, 4mhg_A, 1dux_F, 4uno_A, 3jtg_A, 7jsa_J, 4lg0_B, 4bqa_A, 1bc8_C, 4iri_A, 4l18_B, 1yo5_C, 1awc_A |
| Binding Motifs: | 3wts_AC AGGATGTGGctt 3wts_C aGGa 3wtt_AC gCCACATCCt 3wtu_AC GCCACATCCT 3wtv_AC AGGATGTGGC 3wtw_AC GCCACATCCT |
| Binding Sites: | 3wts_D / 3wtt_D / 3wtu_D / 3wtv_D / 3wtw_D 3wts_E / 3wtt_E / 3wtu_E / 3wtv_E / 3wtw_E |
| Publications: | Shiina M, Hamada K, Inoue-Bungo T, Shimamura M, Uchiyama A, Baba S, Sato K, Yamamoto M, Ogata K. A Novel Allosteric Mechanism on Protein-DNA Interactions underlying the Phosphorylation-Dependent Regulation of Ets1 Target Gene Expressions. Journal of molecular biology 427:1655-69 (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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