Transcription Factor

Accessions: O60806 (JASPAR 2024)
Names: T-box factor, pituitary, T-box protein 19, T-box transcription factor TBX19, TBX19_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: O60806
Length: 448
Pfam Domains: 43-218 T-box
Sequence:
(in bold interface residues)
1 MAMSELGTRKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNE 60
61 MIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHS 120
121 CVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRM 180
181 VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTY 240
241 SHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHR 300
301 NHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTIS 360
361 NGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420
421 WTAVASHPFAGWGGPGAGGHHSPSSLDG
Interface Residues: 29, 32, 33, 36, 37, 68, 195, 196, 212, 215, 216
3D-footprint Homologues: 5flv_I, 1xbr_B, 6f59_B, 2x6v_A, 4a04_B, 1h6f_B
Binding Motifs: MA0804.1 wtTmrCACcTAgGTGygAaa
MA0804.2 TmrCACcTAgGTGygAa
Publications: Wilson V, Conlon FL. The T-box family. Genome Biol : (2002;3(6):REVIEWS3008.). [Pubmed]
Related annotations: PaperBLAST

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