Transcription Factor
Accessions: | Q9ULV5 (JASPAR 2024) |
Names: | Heat shock factor protein 4, Heat shock transcription factor 4, hHSF4, HSF 4, HSF4_HUMAN, HSTF 4 |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | Q9ULV5 |
Length: | 492 |
Pfam Domains: | 19-121 HSF-type DNA-binding |
Sequence: (in bold interface residues) | 1 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP 60 61 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK 120 121 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ 180 181 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF 240 241 IQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPG 300 301 GDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD 360 361 RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ 420 421 PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT 480 481 ASYLGPEASPSP |
Interface Residues: | 64, 65, 70, 72, 73, 74, 76, 77, 119 |
3D-footprint Homologues: | 5hdn_C, 5d5v_B, 5d5w_B, 3hts_B, 7dci_A |
Binding Motifs: | MA0771.1 TTCtrGAAyrTTC |
Publications: | Funikov SIu, Garbuz DG, Zatsepina OG. [Kinetics of heat shock response upon disfunction of general transcription factor (HSF)]. Mol Biol (Mosk) 48:306-13 (2014). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.