Transcription Factor
| Accessions: | BACH2 (HT-SELEX2 May2017) |
| Names: | BACH2, ENSG00000112182 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bZIP experiment: HT-SELEX Hamming distance: 2 cycle: 2, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 2 |
| Length: | 133 |
| Pfam Domains: | 55-101 Basic region leucine zipper 56-104 bZIP transcription factor |
| Sequence: (in bold interface residues) | 1 FSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDVRRRSK 60 61 NRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKACMGELLDNFSCLSQEVCR 120 121 DIQSPEQIQALHR |
| Interface Residues: | 57, 60, 61, 62, 64, 65, 68, 69, 72 |
| 3D-footprint Homologues: | 7x5e_E, 2wt7_B, 7x5e_F, 1gd2_G, 1skn_P, 5t01_B, 5vpe_D |
| Binding Motifs: | BACH2_2 awasCATGAsTCATsvtwt BACH2_3 awAbsATGACGTSATsmTWt BACH2_methyl_1 awAscATGAsTCATsrtwt |
| Related annotations: | PaperBLAST |
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