Transcription Factor

Accessions: Q9D2W8 (JASPAR 2024)
Names: NKX63_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 262
Pfam Domains: 141-197 Homeobox domain
Sequence:
(in bold interface residues)
1 MESNLQGTFLLNNTQLAQFSEMKAPMCQYSVQNSFYKLSPPGLGPQLAAGTPHGITDILS 60
61 RPVATPNSSLLSGYPHVAGFGGLSSQGVYYGPQVGSFSKAGNEYPTRTRNCWADTGQDWR 120
121 GSARPCSNTPDPLSDTIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMT 180
181 ESQVKVWFQNRRTKWRKKSALEPSSSTPRAPGGASGDRAASENEDDEYNKPLDPDSDDEK 240
241 IRLLLRKHRAAFSVLSLGAHSV
Interface Residues: 141, 142, 143, 144, 182, 183, 185, 186, 189, 190, 193, 194, 197
3D-footprint Homologues: 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 3d1n_M, 1zq3_P, 2lkx_A, 1nk2_P, 2ld5_A, 7q3o_C, 6es3_K, 1ig7_A, 7psx_B, 5hod_A, 3l1p_A, 3a01_E, 1jgg_B, 5jlw_D, 3lnq_A, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 6m3d_C, 5flv_I, 2hos_A, 1b72_A, 5zjt_E, 4cyc_A, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 1au7_A, 1o4x_A, 1du0_A, 4qtr_D, 1puf_B, 8g87_X
Binding Motifs: PH0120.1 gawwwTTAATKAmtkyk
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.