Transcription Factor

Accessions: Dref (DrosophilaTF 1.1)
Names: DNA replication-related element factor, DREF, FI03642p, Q94883_DROME
Organisms: Drosophila melanogaster
Libraries: DrosophilaTF 1.1 1
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]
Length: 709
Pfam Domains: 35-84 BED zinc finger
Sequence:
(in bold interface residues)
1 MSEGVPASPVAIGELKYEDVSQLNFSKLYSPKMKSVYWRYFGFPSNDNNEVITKQNVVCI 60
61 KCHKVLTNHGNTTNLRAHLQHRHKDLFKELCQEHDIHVPPRKTPRNVSHPPLSKRNVSSR 120
121 RVKLEFINNRNHDNASDDELDEAAVATAAMQAEEDASSQTMLYETMVPFTYDEAENLVEE 180
181 EERLVMEPKYGRKRKVATPSSALMHGRVIKHEEGGYAAVANIANLAEALTDIVIKDLRNV 240
241 DSLYDAGFGEFLRQVLGNSAAMPEPHKIDSLINEMHASKFLEIGEITRDFTSEKPFSLAF 300
301 EMWVNVEQRRFLSIFHHFLDEETHSVRGMLYATVEYNDYIVFDDLLTDFYLANCTLAIIN 360
361 YDEEEDLLHTYLREKNIPISLCYVSVIDKCLRRVFEIEEVATLLEQVKDLMQRHSTEIAS 420
421 KVSEVPMPTYNEHFPWTLYETLKFFAESISWSEDMDHLVISAKTVTEALSALVIALDTLR 480
481 GEDIPLCSMLSPITSKILIKKLGIAEQDDPLMMNLKRTISSVLQAHVISNDNLTAAALLD 540
541 PRFHRLTTIDNLERTVRMLTHKYNINFGGVGEGESNEVAATSSVVAIKSEPRVVDGSAPK 600
601 KLGLKLLFDSNEIPNPPKRDADSSVESDLKRYRNEVVVQLDESPIEWWLKMGHIYGTLRD 660
661 LASLYHSVPGVVTLSFKKALRDQIYDFNKRFMLTGSHIDAILFLHHHNN
Interface Residues: 266, 395
3D-footprint Homologues: 6dta_B, 6sxb_G
Binding Motifs: Dref TATCGATA
Publications: Hirose F., Yamaguchi M., Handa H., Inomata Y., Matsukage A. Novel 8-base pair sequence (Drosophila DNA replication-related element) and specific binding factor involved in the expression of Drosophila genes for DNA polymerase alpha and proliferating cell nuclear antigen. J. Biol. Chem. 268:2092-2099 (1993). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.