Transcription Factor
| Accessions: | UP00240A (UniPROBE 20160601) |
| Names: | caudal type homeo box 1, Caudal-type homeobox protein 1, Cdx-1, Cdx1, Homeobox protein CDX-1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P18111 |
| Description: | caudal type homeo box 1 |
| Length: | 93 |
| Pfam Domains: | 18-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 SVAAAGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQV 60 61 KIWFQNRRAKERKVNKKKQQQQQPLPPTQLPLP |
| Interface Residues: | 14, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73 |
| 3D-footprint Homologues: | 1puf_A, 3d1n_M, 1nk2_P, 3lnq_A, 1jgg_B, 6es3_K, 2ld5_A, 7q3o_C, 4xrs_G, 2hos_A, 1fjl_B, 5zfz_A, 4cyc_A, 6m3d_C, 5flv_I, 3l1p_A, 1ig7_A, 3a01_E, 2h1k_B, 7psx_B, 2lkx_A, 6a8r_A, 3cmy_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1au7_A, 7xrc_C, 2xsd_C, 1le8_A, 1e3o_C, 1k61_B, 1zq3_P, 1b72_A, 1o4x_A, 8g87_X, 5zjt_E, 4qtr_D, 1le8_B, 1du0_A, 5hod_A, 4xrm_B, 1mnm_C, 1puf_B |
| Binding Motifs: | UP00240A_1 wrmGGYmATWAAatkw |
| Binding Sites: | TAATAAAA GGTAATTA AATAAAAT ACCATAAA AGTAATTA ATAATAAA ATAATTAC ATCATAAA ATTAATTA ATTTATGA CAATAAAA CCATAAAA GCAATAAA GCAATTAA GCCATAAA GTAATAAA GTAATTAA GTCATAAA TAATTAAA TCATAAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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