Transcription Factor

						

			
Accessions: V6CLN5 (JASPAR 2024)

			
Names: V6CLN5_CAEEL
Organisms: Caenorhabditis elegans
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: V6CLN5
Length: 1615
Pfam Domains:   103-125 Zinc finger, C2H2 type
  157-181 Zinc-finger of C2H2 type
  157-178 C2H2-type zinc-finger domain
  256-278 C2H2-type zinc-finger domain
  472-494 C2H2-type zinc finger
  525-548 Zinc-finger of C2H2 type
  525-603 C2H2 type zinc-finger (2 copies)
  526-544 C2H2-type zinc finger
  574-598 Zinc finger, C2H2 type
  574-595 C2H2-type zinc finger
  856-912 Homeobox domain
1032-1088 Homeobox domain
1110-1131 C2H2-type zinc finger
1227-1256 C2H2 type zinc-finger (2 copies)
1339-1395 Homeobox domain
1408-1438 C2H2 type zinc-finger (2 copies)
1409-1428 Zinc-finger of C2H2 type
1410-1428 C2H2-type zinc finger
1546-1567 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MDVALLTMDDNNKPPTSSESTESRETSPPMMPDSAEIMRLLTDPSTAQMFANENTKCQLG   60
  61 RILAASGFDEASLSSSFPFDPTLGAFADISQFSSLRNSSKTLKCPKCNWHYKYQETLEIH  120
 121 MKEKHNDVDVKCMFCAENRPHPKLARGETYSCGYKPYRCDLCRYSTTTKGNLSIHMQSDK  180
 181 HLHAVQELPNSIEFAANFACGAPVSRSSPIEESDGSLVCLICGIFATESIAEMMEHVEQD  240
 241 RSRTFQGDVTVLNGSFRCHLCPYNTTLKANFQLHTRTDKHLQKVQIANHLREGTRPHTAI  300
 301 YRLSSTKTSVQVLCRQCQEVISSGESLREHRHFHALLAAKQRLWRCKLCRLEFDSVLLAA  360
 361 GHMTCHEPSTWPNESLDFKTMEDAAYACAGCEFTTKDVSDFEEHAKGHEEEAGASSQKAC  420
 421 ALCLEPTDDLEKHLVEQHRIAESAIEKFLLTERTAKEASCSSSSEPSSEFAHRCSRCSMA  480
 481 FRSESQLQTHSLQHVFNTFHKCPTCGDSFDENTIVTHMLEHTKEECEMCSETFATKEAFL  540
 541 SHLNSARHLQQAKKQLENSLVDLNSQDVEKQRIYVCNVCKQSYPQAANLDVHMRSMTHQS  600
 601 RMSRLSELVATGELNGEKAVFEQPGIPAPTINSFIETTTNQSSLNDLMSLLTRSESDEIR  660
 661 EEVNGLQVMTQIKVYGESKITSLVPELAGKIDNIALFDDSRAAEVSKIDCSACGQQISGI  720
 721 LALNLHYEESHSSKIPSDVLRKFGERLLAALEDGLSRENSVKNGSQSPLSNDDEPMEKKM  780
 781 RLENMLPEMDKNAAASQFAMFQQMMNCFPFMAPPGTSSGNFGFSPEMINQLMNPAAAAAA  840
 841 ATAAAAAHAANNSPAKRARTRITDDQLKVLRQYFNINNSPSEAQIKEMSQKASLPEKVIK  900
 901 HWFRNTLFKERQRDKDSPYNFSIPPQMGIDLDIYEKTGETKVLSLSNEAPKSELSSARAT  960
 961 PTIPTPIPLIVEEKKPEPKSQTPSSSSSQLNLQAMLSQMQGSFFDASNFMSASVNPMTPS 1020
1021 TPSCNTSSSGRRANRTRFTDFQLRTLQQFFDKQAYPKDDDLEALSKKLQLSPRVIVVWFQ 1080
1081 NARQKARKIYENQPNHESSDRFVRTPGSNFQCKRCSQVFQRYYELIQHQQKKCYKDDVAA 1140
1141 LASDNKSVEESLTEEEKSQLLAQQQVAQLASTLELPKFQPAELLKMIGANSVTPSSSAAS 1200
1201 QKSSNDVLLKMCESIVGGSTPSTSSFHKLCIFCAQDFKDRSAMSEHMAQKHPQHMLLPNF 1260
1261 DLDMMPDAGGAELLMDLKDSALDLSGSSVDYRDSISTSPSRSEDDVLTEALDDSAFAAFG 1320
1321 LQLANSTSGSECRSPASNKRFRTHLTPMQVQMMKSVFNEYKTPSMAECELLGKEVGLHKR 1380
1381 VVQVWFQNARAKERKTRGAVDEDSRSGELHCEICDKTFATRLSLQDHLFAEQHIEFLRNN 1440
1441 LKREGVSELTTASVTECSPEKKAKLPNPLDLASFPFLNTFDIQIYGTPIAFLQVPDEIKK 1500
1501 QITDDITAGKSRTTFSQDGFPLDKLKESLPEDEKSNLTVTQKDVGWACPACTFVFQEEKK 1560
1561 LREHQKAMCQSDKTLTLVQTHYSCKSCQSDFCLQSEYQFHLSMPPHTTTTTTTTP
Interface Residues: 113, 115, 116, 119, 140, 141, 142, 143, 146, 168, 169, 170, 171, 173, 174, 378, 397, 399, 400, 403, 429, 431, 432, 447, 482, 483, 484, 485, 486, 489, 490, 492, 510, 511, 512, 513, 514, 516, 517, 519, 521, 524, 531, 533, 534, 535, 536, 537, 538, 541, 542, 543, 544, 545, 547, 550, 551, 553, 554, 555, 557, 558, 559, 561, 567, 569, 570, 572, 573, 585, 586, 587, 588, 590, 591, 857, 858, 859, 901, 904, 905, 908, 909, 912, 1032, 1033, 1034, 1035, 1073, 1074, 1076, 1077, 1080, 1081, 1084, 1085, 1086, 1088, 1339, 1340, 1341, 1342, 1383, 1384, 1387, 1388, 1391, 1392, 1395
3D-footprint Homologues: 5und_A, 8gn3_A, 8h9h_G, 3uk3_C, 7y3l_A, 6u9q_A, 8ssq_A, 8ssu_A, 2kmk_A, 8cuc_F, 7w1m_H, 1ubd_C, 5kkq_D, 7eyi_G, 1mey_C, 5ei9_F, 7n5w_A, 2gli_A, 5k5i_A, 4m9v_C, 7ysf_A, 7y3m_I, 2i13_A, 6ml4_A, 5yj3_D, 7txc_E, 5v3j_F, 1jgg_B, 6m3d_C, 1b72_A, 1puf_B, 2h1k_B, 1puf_A, 1fjl_B, 1ig7_A, 3cmy_A, 1zq3_P, 1nk2_P, 2ld5_A, 5flv_I, 3rkq_B, 2r5y_A, 7psx_B, 4xrs_G, 2d5v_B, 5zjt_E, 5jlw_D, 4cyc_A, 3a01_E, 3lnq_A, 7xrc_C, 1le8_A, 2xsd_C, 3d1n_M, 5zfz_A, 6a8r_A, 2lkx_A, 6es3_K, 7q3o_C, 6wig_A, 5hod_A, 1au7_A, 2hdd_A, 3l1p_A, 2hos_A, 1e3o_C, 1o4x_A, 4qtr_D, 8g87_X, 1du0_A
Binding Motifs: MA0928.1 artTAATTAgd
MA0928.2 tTAATTAg
			
Publications: Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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