Transcription Factor

						

			
Accessions: Q9UH92 (JASPAR 2024)

			
Names: bHLHd13, Class D basic helix-loop-helix protein 13, Max-like bHLHZip protein, Max-like protein X, MLX_HUMAN, Protein BigMax, Transcription factor-like protein 4
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9UH92
Length: 298
Pfam Domains:   130-187 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MTEPGASPEDPWVKASPVGAHAGEGRAGRARARRGAGRRGASLLSPKSPTLSVPRGCRED   60
  61 SSHPACAKVEYAYSDNSLDPGLFVESTRKGSVVSRANSIGSTSASSVPNTDDEDSDYHQE  120
 121 AYKESYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKT  180
 181 IDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAHQDNPHEGEDQVSDQVKFN  240
 241 VFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCKPQTLREIVIGVLHQLKNQLY
Interface Residues: 131, 132, 133, 134, 135, 136, 137, 138, 139, 141, 142, 146, 168
3D-footprint Homologues: 1a0a_B, 7z5k_B, 2ypa_A, 1an4_A, 7d8t_A, 4zpk_A, 7xq5_A, 5nj8_D, 7f2f_B, 5v0l_A, 4h10_A, 5gnj_I, 1am9_A, 8osl_O, 6g1l_A, 4h10_B, 7xi3_A, 5i50_B, 5eyo_A, 7rcu_E, 8osl_P
Binding Motifs: MA0663.1 rTCACGTGAt
			
Publications: Stoeckman AK, Ma L, Towle HC. Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes. J Biol Chem 279:15662-9 (2004). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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