Transcription Factor
| Accessions: | P70396 (JASPAR 2024) |
| Names: | DLX5_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 289 |
| Pfam Domains: | 32-117 Homeobox protein distal-less-like N terminal 138-194 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MTGVFDRRVPSIRSGDFQAPFPTSAAMHHPSQESPTLPESSATDSDYYSPAGAAPHGYCS 60 61 PTSASYGKALNPYQYQYHGVNGSAAGYPAKAYADYGYASPYHQYGGAYNRVPSATSQPEK 120 121 EVAEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQ 180 181 VKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAH 240 241 PPTSNQSPASSYLENSASWYPSAASSINSHLPPPGSLQHPLALASGTLY |
| Interface Residues: | 138, 139, 140, 141, 179, 180, 182, 183, 186, 187, 190, 191, 194 |
| 3D-footprint Homologues: | 3d1n_M, 1fjl_B, 5zfz_A, 2h1k_B, 1puf_A, 1ig7_A, 5zjt_E, 3cmy_A, 1mnm_C, 6a8r_A, 1nk2_P, 1zq3_P, 6m3d_C, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 2hos_A, 5jlw_D, 4cyc_A, 1au7_A, 4xrs_G, 4j19_B, 3a01_E, 1b72_A, 5flv_I, 3lnq_A, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 1jgg_B, 1e3o_C, 2xsd_C, 7xrc_C, 1le8_A, 4xrm_B, 1k61_B, 3l1p_A, 1o4x_A, 8g87_X, 4qtr_D, 1du0_A, 1puf_B |
| Binding Motifs: | PH0024.1 ssrgyAATTrsykmts MA1476.2 wwGCAATTAgmw MA1476.3 GCAATTAg |
| Binding Sites: | MA1476.3.13 / MA1476.3.15 / MA1476.3.19 / MA1476.3.5 MA1476.2.1 / MA1476.2.3 MA1476.2.11 / MA1476.2.7 MA1476.2.14 / MA1476.2.9 MA1476.2.10 / MA1476.2.15 MA1476.2.11 / MA1476.2.16 MA1476.2.14 / MA1476.2.19 MA1476.2.2 / MA1476.2.4 MA1476.2.3 / MA1476.2.5 MA1476.2.6 / MA1476.2.8 MA1476.2.12 / MA1476.2.17 MA1476.2.13 / MA1476.2.18 MA1476.2.15 / MA1476.2.20 MA1476.2.16 MA1476.2.17 MA1476.2.18 MA1476.2.19 MA1476.2.20 MA1476.2.4 / MA1476.2.6 MA1476.2.5 / MA1476.2.7 MA1476.2.13 / MA1476.2.8 MA1476.2.1 MA1476.2.2 MA1476.2.12 MA1476.3.1 / MA1476.3.12 / MA1476.3.4 MA1476.3.16 / MA1476.3.8 MA1476.3.7 MA1476.3.10 / MA1476.3.18 / MA1476.3.9 MA1476.3.17 MA1476.3.3 MA1476.3.11 MA1476.3.14 MA1476.3.2 MA1476.3.20 / MA1476.3.6 MA1476.2.10 MA1476.2.9 |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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