Transcription Factor
| Accessions: | UP00468A (UniPROBE 20160601), Q00947 (JASPAR 2024) |
| Names: | BAP1, Species-specific tRNA Processing, SSY2, Stp1, STP1_YEAST |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Description: | Species-specific tRNA Processing : Transcription factor, undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing |
| Length: | 519 |
| Pfam Domains: | 160-182 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MPSTTLLFPQKHIRAIPGKIYAFFRELVSGVIISKPDLSHHYSCENATKEEGKDAADEEK 60 61 TTTSLFPESNNIDRSLNGGCSVIPCSMDVSDLNTPISITLSPENRIKSEVNAKSLLGSRP 120 121 EQDTGAPIKMSTGVTSSPLSPSGSTPEHSTKVLNNGEEEFICHYCDATFRIRGYLTRHIK 180 181 KHAIEKAYHCPFFNSATPPDLRCHNSGGFSRRDTYKTHLKARHVLYPKGVKPQDRNKSSG 240 241 HCAQCGEYFSTIENFVENHIESGDCKALPQGYTKKNEKRSGKLRKIKTSNGHSRFISTSQ 300 301 SVVEPKVLFNKDAVEAMTIVANNSSGNDIISKYGNNKLMLNSENFKVDIPKRKRKYIKKK 360 361 QQQVSGSTVTTPEVATQNNQEVAPDEISSATIFSPFDTHLLEPVPSSSSESSAEVMFHGK 420 421 QMKNFLIDINSFTNQQQQAQDNPSFLPLDIEQSSYDLSEDAMSYPIISTQSNRDCTQYDN 480 481 TKISQILQSQLNPEYLSENHMRETQQYLNFYNDNFGSQF |
| Interface Residues: | 141, 144, 147, 153, 170, 171, 172, 173, 174, 176, 177, 178, 179, 180, 183, 197, 199, 200, 201, 202, 203, 210, 211, 212, 213, 214, 215, 216, 217, 218, 221, 222, 224, 225, 250, 251, 253, 254, 255 |
| 3D-footprint Homologues: | 6e94_A, 7w1m_H, 3uk3_C, 7ysf_A, 6ml4_A, 7n5w_A, 1g2f_F, 7txc_E, 6blw_A, 2wbs_A, 1llm_D, 8ssq_A, 6wmi_A, 5ei9_F, 2i13_A, 1mey_C, 5kkq_D, 1f2i_J, 1ubd_C, 2lt7_A, 6u9q_A, 4x9j_A, 7eyi_G, 4m9v_C, 8h9h_G, 2jpa_A, 5yel_A, 2gli_A |
| Binding Motifs: | UP00468A_1 tcatatmGyGCCGYryscabrwb MA0394.1 yGCGGCkb |
| Binding Sites: | ACGGCGCG ATACGGCG CACGGCAC CACGGCGC CGCCGTAC CGCCGTGC CGCGGCAC GCGCCGCA GCGCCGTA GTGCCGTA ACACGGCA ACACGGCG ACGCGGCG ACGGCACT ACGGCGCC CGCACGGC CGCCGCGC CGCGGCGC GCACGGCA GCCGTGCC |
| Publications: | Gordân R, Murphy KF, McCord RP, Zhu C, Vedenko A, Bulyk ML. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol : (2011). [Pubmed] MacIsaac K.D, Wang T, Gordon D.B, Gifford D.K, Stormo G.D, Fraenkel E. An improved map of conserved regulatory sites for Saccharomyces cerevisiae. BMC bioinformatics 7:113 (2006). [Pubmed] |
| Related annotations: | PaperBLAST |
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