Transcription Factor

						

			
Accessions: P17544 (JASPAR 2024)

			
Names: Activating transcription factor 7, ATF7_HUMAN, cAMP-dependent transcription factor ATF-7, Cyclic AMP-dependent transcription factor ATF-7, Transcription factor ATF-A
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 494
Pfam Domains:   342-395 Basic region leucine zipper
  343-402 bZIP transcription factor
Sequence: 
(in bold interface residues)		   1 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN   60
  61 CEEVGLFNELASSFEHEFKKAADEDEKKARSRTVAKKLVAAAGPLDMSLPSTPDIKIKEE  120
 121 EPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTL  180
 181 PSPTSVITQAPPSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVP  240
 241 NIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTAR  300
 301 PEQSQILIQHPDAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRC  360
 361 RQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQG  420
 421 YLESPKESSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQ  480
 481 SHVIMTPQSQSAGR
Interface Residues: 20, 21, 22, 23, 25, 26, 28, 29, 30, 348, 349, 353, 354, 356, 357, 360, 361
3D-footprint Homologues: 1g2f_F, 7n5w_A, 5yj3_D, 1ubd_C, 8cuc_F, 2wbs_A, 1mey_C, 6a57_A, 4x9j_A, 8h9h_G, 6wmi_A, 7y3l_A, 6blw_A, 5ei9_F, 2gli_A, 1f2i_J, 7eyi_G, 7y3m_I, 6jnm_A, 5kl3_A, 1tf3_A, 2jpa_A, 7x5e_E, 4eot_A, 2wt7_A, 2wt7_B, 6mg1_B, 5t01_B, 2dgc_A, 1dh3_C, 5vpe_C, 1nwq_C, 5vpe_D
Binding Motifs: MA0834.1 crATGACGTCAYmv
MA0834.2 ATGACGTCAY
			
Publications: Hai T., Liu F., Coukos W. J., Green M. R. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev. 3:2083-2090 (1989). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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