Transcription Factor

						

			
Accessions: O14948 (JASPAR 2024)

			
Names: bHLHe34, Class E basic helix-loop-helix protein 34, hTFEC-L, TFE-C, TFEC_HUMAN, Transcription factor EC, Transcription factor EC-like
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: O14948
Length: 347
Pfam Domains:   140-193 Helix-loop-helix DNA-binding domain
  225-345 Domain of unknown function (DUF3371)
Sequence: 
(in bold interface residues)		   1 MTLDHQIINPTLKWSQPAVPSGGPLVQHAHTTLDSDAGLTENPLTKLLAIGKEDDNAQWH   60
  61 MEDVIEDIIGMESSFKEEGADSPLLMQRTLSGSILDVYSGEQGISPINMGLTSASCPSSL  120
 121 PMKREITETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGT  180
 181 ILKASVEYIKWLQKEQQRARELEHRQKKLEQANRRLLLRIQELEIQARTHGLPTLASLGT  240
 241 VDLGAHVTKQQSHPEQNSVDYCQQLTVSQGPSPELCDQAIAFSDPLSYFTDLSFSAALKE  300
 301 EQRLDGMLLDDTISPFGTDPLLSATSPAVSKESSRRSSFSSDDGDEL
Interface Residues: 141, 143, 144, 145, 147, 148, 151, 152, 176, 178
3D-footprint Homologues: 1a0a_B, 1an4_A, 4zpk_A, 7ssa_L, 6g1l_A, 5eyo_A, 1am9_A, 7xi3_A, 5nj8_D, 4h10_A, 7d8t_A, 5gnj_I, 8osl_O, 5v0l_A, 4h10_B, 7f2f_B, 5i50_B, 2ypa_B, 2ypa_A, 8osl_P, 5nj8_C, 5v0l_B
Binding Motifs: MA0871.1 rtCACrTGAy
MA0871.2 msCACGTGACc
MA0871.3 CACGTGAC
			
Publications: Jones S. An overview of the basic helix-loop-helix proteins. Genome Biol : (2004;5(6):226.). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.