Transcription Factor
| Accessions: | HINFP_HUMAN (HOCOMOCO 10), Q9BQA5 (JASPAR 2024) |
| Names: | HiNF-P, HINFP_HUMAN, Histone H4 transcription factor, Histone nuclear factor P, MBD2-interacting zinc finger protein, Methyl-CpG-binding protein 2-interacting zinc finger protein |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9BQA5 |
| Length: | 517 |
| Pfam Domains: | 186-210 Zinc-finger double domain 229-251 Zinc finger, C2H2 type 229-251 C2H2-type zinc finger 255-275 C2H2-type zinc finger 255-278 Zinc finger, C2H2 type 269-295 Zinc-finger double domain 345-368 C2H2-type zinc finger 345-368 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MPPPGKVPRKENLWLQCEWGSCSFVCSTMEKFFEHVTQHLQQHLHGSGEEEEEEEEDDPL 60 61 EEEFSCLWQECGFCSLDSSADLIRHVYFHCYHTKLKQWGLQALQSQADLGPCILDFQSRN 120 121 VIPDIPDHFLCLWEHCENSFDNPEWFYRHVEAHSLCCEYEAVGKDNPVVLCGWKGCTCTF 180 181 KDRSKLREHLRSHTQEKVVACPTCGGMFANNTKFLDHIRRQTSLDQQHFQCSHCSKRFAT 240 241 ERLLRDHMRNHVNHYKCPLCDMTCPLPSSLRNHMRFRHSEDRPFKCDCCDYSCKNLIDLQ 300 301 KHLDTHSEEPAYRCDFENCTFSARSLCSIKSHYRKVHEGDSEPRYKCHVCDKCFTRGNNL 360 361 TVHLRKKHQFKWPSGHPRFRYKEHEDGYMRLQLVRYESVELTQQLLRQPQEGSGLGTSLN 420 421 ESSLQGIILETVPGEPGRKEEEEEGKGSEGTALSASQDNPSSVIHVVNQTNAQGQQEIVY 480 481 YVLSEAPGEPPPAPEPPSGGIMEKLQGIAEEPEIQMV |
| Interface Residues: | 145, 154, 155, 181, 182, 183, 184, 185, 188, 189, 209, 210, 211, 212, 213, 214, 215, 216, 217, 220, 239, 240, 241, 242, 243, 245, 246, 265, 266, 267, 268, 269, 271, 272, 276, 284, 293, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 307, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 335, 355, 356, 357, 358, 359, 362 |
| 3D-footprint Homologues: | 6a57_A, 6jnm_A, 8cuc_F, 1mey_C, 5kl3_A, 2gli_A, 1g2f_F, 7eyi_G, 4x9j_A, 1llm_D, 7n5w_A, 8h9h_G, 4m9v_C, 7y3m_I, 6e94_A, 8ssq_A, 2i13_A, 1ubd_C, 2wbs_A, 5yel_A, 5ei9_F, 7txc_E, 1f2i_J, 7w1m_H, 5k5l_F, 6ml4_A, 3uk3_C, 6wmi_A, 5v3j_F, 7y3l_A, 6u9q_A, 5und_A, 8ssu_A, 8gn3_A, 5kkq_D, 7ysf_A, 2kmk_A, 5yj3_D, 5k5i_A, 6blw_A, 1tf3_A, 2lt7_A, 1tf6_A, 2jpa_A, 2drp_D |
| Binding Motifs: | MA0131.2 carCGTCCGCgk HINFP_HUMAN.H10MO.C|M01212 rmsytmgCGGACGTtv MA0131.1 bwACGTCCGc MA0131.3 rCGTCCGC |
| Binding Sites: | MA0131.1.1 MA0131.1.10 / MA0131.1.9 MA0131.1.11 MA0131.1.12 MA0131.1.13 MA0131.1.14 MA0131.1.15 MA0131.1.16 MA0131.1.17 MA0131.1.18 MA0131.1.19 MA0131.1.2 MA0131.1.20 MA0131.1.3 MA0131.1.4 MA0131.1.5 / MA0131.1.6 MA0131.1.7 / MA0131.1.8 |
| Publications: | Sekimata M, Homma Y. Sequence-specific transcriptional repression by an MBD2-interacting zinc finger protein MIZF. Nucleic acids research 32:590-7 (2004). [Pubmed] |
| Related annotations: | PaperBLAST |
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