Transcription Factor
| Accessions: | T081042_1.02 (CISBP 1.02), A8XJN7 (JASPAR 2024) |
| Names: | Cbr-fkh-2, T081042_1.02;, A8XJN7_CAEBR, FKH02_CAEBR, Forkhead box protein fkh-2, Forkhead transcription factor family member fkh-2 |
| Organisms: | Caenorhabditis briggsae |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Forkhead |
| Length: | 279 |
| Pfam Domains: | 101-196 Fork head domain |
| Sequence: (in bold interface residues) | 1 MARFSILDLCPDLVEKAMNVQNGLVSMQSTLQLQAQKDINDPCTSIDSTTDIMSNPANDN 60 61 SDYLLDESVDDERSESTSSKDSKSPCSNSSDDKKPSSPNDKPPFSYNALIMMAIKNSPEK 120 121 RLTLAGIYDYILTNYPFYRDNKQGWQNSIRHNLSLNKCFVKVPRNFDDPGKGNYWMLDAT 180 181 CEDEVFIGGATGKLRRRPSTLSRARMDAYKQYGAAAANLFPYFNPGLPPMPRTPFITTPP 240 241 TAFLPRPMMPMPSLAPVFTQPELIQMYLNQQQGLFAKLQ |
| Interface Residues: | 141, 144, 146, 147, 148, 150, 151, 152, 154, 155, 164, 171, 197 |
| 3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3qrf_G |
| Binding Motifs: | M0715_1.02 rTAAACAa MA0920.1 rTAAACAa MA0920.2 rTAAACA |
| Publications: | Hedrick SM, Hess Michelini R, Doedens AL, Goldrath AW, Stone EL. FOXO transcription factors throughout T cell biology. Nat Rev Immunol 12:649-61 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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