Transcription Factor

Accessions: P13434 (JASPAR 2024)
Names: HAP3_YEAST, Transcriptional activator HAP3, UAS2 regulatory protein A
Organisms: Saccharomyces cerevisiae
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 144
Pfam Domains: 40-103 Histone-like transcription factor (CBF/NF-Y) and archaeal histone
42-106 Core histone H2A/H2B/H3/H4
Sequence:
(in bold interface residues)
1 MNTNESEHVSTSPEDTQENGGNASSSGSLQQISTLREQDRWLPINNVARLMKNTLPPSAK 60
61 VSKDAKECMQECVSELISFVTSEASDRCAADKRKTINGEDILISLHALGFENYAEVLKIY 120
121 LAKYRQQQALKNQLMYEQDDEEVP
Interface Residues: 45, 60, 63, 120, 133, 135, 136
3D-footprint Homologues: 6r2v_B, 4awl_B, 4g92_B, 7wlr_E, 5t5k_E, 7cvo_B, 2fr4_L, 8b4h_A
Binding Motifs: MA0314.1 tcTsATTGGyyvrra
MA0314.2 kcTGATTGGyyc
MA0314.3 TGATTGGyy
Binding Sites: MA0314.2.1 / MA0314.2.2 / MA0314.2.4 / MA0314.2.5
MA0314.2.10 / MA0314.2.11 / MA0314.2.12 / MA0314.2.9
MA0314.2.10 / MA0314.2.11
MA0314.2.12 / MA0314.2.13
MA0314.2.14 / MA0314.2.15 / MA0314.2.16 / MA0314.2.17 / MA0314.2.18 / MA0314.2.20
MA0314.2.16 / MA0314.2.19
MA0314.2.3 / MA0314.2.4
MA0314.2.5
MA0314.2.6
MA0314.2.7
MA0314.2.8
MA0314.2.9
MA0314.2.13 / MA0314.2.14 / MA0314.2.15 / MA0314.2.17
MA0314.2.3
MA0314.3.1 / MA0314.3.13 / MA0314.3.2 / MA0314.3.4
MA0314.3.10 / MA0314.3.12
MA0314.3.11 / MA0314.3.14 / MA0314.3.15 / MA0314.3.17 / MA0314.3.18 / MA0314.3.20
MA0314.3.16 / MA0314.3.19
MA0314.3.3 / MA0314.3.9
MA0314.3.5
MA0314.3.6
MA0314.3.7
MA0314.3.8
Publications: Pachkov M, Erb I, Molina N, van Nimwegen E. SwissRegulon: a database of genome-wide annotations of regulatory sites. Nucleic acids research 35:D127-31 (2007). [Pubmed]
Related annotations: PaperBLAST

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