Transcription Factor

Accessions: Q9FIM4 (JASPAR 2024), T25608 (AthalianaCistrome v4_May2016)
Names: AtMYB119, MY119_ARATH, Myb-related protein 119, Transcription factor MYB119, AT5G58850, MYB119, T25608;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:MYB
Length: 430
Pfam Domains: 105-151 Myb-like DNA-binding domain
108-166 Myb-like DNA-binding domain
158-199 Myb-like DNA-binding domain
160-207 Myb-like DNA-binding domain
Sequence:
(in bold interface residues)
1 MEDRRLVHGAAPPLTAVERFLYGQKNDALCSKKQESSRDQPIVKTKISIETRSDNKENTT 60
61 FGPTREKHLVLNGGNRNPTGEVVARSAARDYQNSTKKRSSKNLIKGQWTAEEDRKLIRLV 120
121 RQHGERKWAMISEKLEGRAGKQCRERWHNHLRPDIKKDGWSEEEERVLVESHMRIGNKWA 180
181 EIAKLIPGRTENSIKNHWNATKRRQNSKRKHKRESNADNNDRDASPSAKRPCILQDYIKS 240
241 IERNNINKDNDEKKNENTISVISTPNLDQIYSDGDSASSILGGPYDEELDYFQNIFANHP 300
301 ISLENLGLSQTSDEVTQSSSSGFMIKNPNPNLHDSVGIHHQEATITAPANTPHLASDIYL 360
361 SYLLNGTTSSYSDTHFPSSSSSTSSTTVEHGGHNEFLEPQANSTSERREMDLIEMLSGSI 420
421 QGSNICFPLV
Interface Residues: 105, 106, 139, 140, 141, 142, 144, 145, 148, 149, 150, 152, 154, 156, 191, 192, 195, 196, 199, 200, 201, 213
3D-footprint Homologues: 3osg_A, 1vfc_A, 2kdz_A, 7xur_A, 1w0t_A, 1mse_C, 6kks_A, 3zqc_A, 5eyb_B, 8ity_W, 5n9g_C
Binding Motifs: M0517 / MA1176.1 yrwmCGTTACr
M0510 wwwwyGTAACGkwyr
MA1176.2 rwmCGTTACr
Binding Sites: MA1176.1.1
MA1176.1.10
MA1176.1.11
MA1176.1.12
MA1176.1.13
MA1176.1.14
MA1176.1.15
MA1176.1.16
MA1176.1.17
MA1176.1.18
MA1176.1.19
MA1176.1.2
MA1176.1.20
MA1176.1.3
MA1176.1.4
MA1176.1.5
MA1176.1.6
MA1176.1.7 / MA1176.1.9
MA1176.1.8
MA1176.2.15
MA1176.2.1
MA1176.2.10
MA1176.2.11
MA1176.2.12
MA1176.2.13
MA1176.2.14
MA1176.2.16
MA1176.2.17
MA1176.2.18
MA1176.2.19
MA1176.2.2
MA1176.2.20
MA1176.2.3
MA1176.2.4
MA1176.2.5
MA1176.2.6
MA1176.2.7 / MA1176.2.9
MA1176.2.8
Publications: Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Related annotations: PaperBLAST

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