Transcription Factor
| Accessions: | ATOH1 (HT-SELEX2 May2017) |
| Names: | ATOH1, ENSG00000172238 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bHLH experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: bHLH experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2 |
| Length: | 114 |
| Pfam Domains: | 27-78 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 GVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDK 60 61 KLSKYETLQMAQIYINALSELLQTPSGGEQPPPPPASCKSDHHHLRTAASYEGG |
| Interface Residues: | 28, 30, 31, 32, 34, 35, 36, 38, 39, 64 |
| 3D-footprint Homologues: | 7z5k_B, 2ypa_A, 1an4_A, 5eyo_A, 6od3_F, 7d8t_A, 5i50_B, 7ssa_L, 6g1l_A, 2ypa_B, 2ql2_A, 2ql2_D, 8osl_P, 5gnj_I, 4h10_A |
| Binding Motifs: | ATOH1_3 amCATATGky ATOH1_4 AACAGCTGTY ATOH1_methyl_1 AmCATATGky ATOH1_methyl_2 AACAGCTGTy |
| Related annotations: | PaperBLAST |
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