Transcription Factor

						

			
Accessions: Q9GZN2 (JASPAR 2024)

			
Names: 5'-TG-3'-interacting factor 2, Homeobox protein TGIF2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2, TGIF2_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 237
Pfam Domains:     19-75 Homeobox domain
    36-75 Homeobox KN domain
Sequence: 
(in bold interface residues)		   1 MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNL   60
  61 SVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSVLAVSVPA  120
 121 PTNVLSLSVCSMPLHSGQGEKPAAPFPRGELESPKPLVTPGSTLTLLTRAEAGSPTGGLF  180
 181 NTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSENPQ
Interface Residues: 18, 19, 20, 21, 22, 23, 24, 63, 64, 67, 70, 71, 72, 74, 75
3D-footprint Homologues: 2h1k_B, 6fqp_B, 2ld5_A, 1mnm_C, 5zjt_E, 1puf_B, 1k61_B, 1le8_B, 2d5v_B, 6fqq_E, 1du0_A, 4xrm_B, 7psx_B, 2hdd_A, 1fjl_B, 2hos_A
Binding Motifs: MA0797.1 TGACAGsTGTCA
			
Publications: Bertolino E., Reimund B., Wildt-Perinic D., Clerc R. G. A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif. J. Biol. Chem. 270:31178-31188 (1995). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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