Transcription Factor

Accessions: Q24533 (JASPAR 2024)
Names: DICH_DROME, Protein fish-hook, SOX domain-containing protein dichaete
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 382
Pfam Domains: 142-210 HMG (high mobility group) box
143-202 Domain of unknown function (DUF1898)
Sequence:
(in bold interface residues)
1 MATLSTHPNYGFHLGQAQGLEDYAPQSQLQLSPGMDMDIKRVLHYSQSLAAMGGSPNGPA 60
61 GQGVNGSSGMGHHMSSHMTPHHMHQAVSAQQTLSPNSSIGSAGSLGSQSSLGSNGSGLNS 120
121 SSGHQSAGMHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEW 180
181 KLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGPQGGLQMQAGGMGQQK 240
241 LGAGPGAGAGGYNPFHQLPPYFAPSHHLDQGYPVPYFGGFDPLALSKLHQSQAAAAAAVN 300
301 NQGQQQGQAPPQLPPTSLSSFYSGIYSGISAPSLYAAHSANAAGLYPSSSTSSPGSSPGT 360
361 ITPNGMDGSMDSALRRPVPVLY
Interface Residues: 70, 144, 147, 149, 150, 153, 157, 168, 169, 170, 173, 211, 213, 215, 239, 245, 249, 272, 292, 316
3D-footprint Homologues: 6rks_A, 2xcr_U, 5iwi_C, 4y60_C, 2lef_A, 1o4x_B, 7m5w_A, 3u2b_C, 1qrv_A, 3f27_D, 4s2q_D, 2gzk_A, 6jrp_D, 3tmm_A, 1j5n_A, 3tq6_B, 1hry_A, 1ckt_A, 7zie_A, 5fhd_A
Binding Motifs: MA0445.1 yCyWTTGTTyT
Binding Sites: MA0445.1.1
MA0445.1.10 / MA0445.1.13
MA0445.1.11
MA0445.1.12
MA0445.1.14
MA0445.1.15
MA0445.1.16
MA0445.1.17
MA0445.1.18
MA0445.1.19
MA0445.1.2
MA0445.1.20 / MA0445.1.4
MA0445.1.3
MA0445.1.5
MA0445.1.6 / MA0445.1.8
MA0445.1.7
MA0445.1.9
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.