Transcription Factor
| Accessions: | T161891_1.02 (CISBP 1.02), P46954 (JASPAR 2024) |
| Names: | SIP4, T161891_1.02;, SIP4_YEAST |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Zinc cluster |
| Length: | 829 |
| Pfam Domains: | 44-81 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 MAKRKYGRSYSLDDTDSCSNKVLIVPTGQSSSNAITDFSVRKAHACDRCRLKKIKCDGLK 60 61 PNCSNCAKIDFPCKTSDKLSRRGLPKGYTELLEKEVVRLTNMNASSSANANSNLPFINDT 120 121 FYCFDNYNTQSENQRFLGHLTWNILTNTFPTQKAVVFTDDRNNIDLQLQLLTNFLNLNGD 180 181 FNHLPNFLLLKYDYNLQFLKNLLSVIIKDFFKRQNSLLLLLYPTNLWKNLLLDKINSTAM 240 241 TGEPITLLALLYIIQFTWSCFDDFKLFKVTKLIVSLTTNSKLDLKVLQLVNLSIFYFMGA 300 301 SVDSCKSKSSLTEHSNVNSVIWTNDLLNLNFTNILNMGLYINPKNLIPISGNNNNNKSNE 360 361 EDDRIVTFWCFQFLSSWWSLIQGLPKSNFLTEEFQPKSISVLEIPRLKPFEILLNFIIYS 420 421 LDGCNLLNISSLNVSDPNFQFFQNELESFKKNLLLWNLYHNLSDHDNFRFLTSSSNKKLT 480 481 TNLLLKNLTGLNHKLNQPDFVEIQLTLFYLSLKLMTLKEGDQDLKKEDISLEILSLYFLI 540 541 LTDDSNNDDNQQLQPQQLNLYHFTPFNSIDIIDLCLNNLNNWSLSLKYESGQNQPHSSKI 600 601 KFEKFQNFLNHWCPIWYYDEFSTNPFLQILKINFKLLPFETIHYSQEEQRLLISLNKLRY 660 661 LDAVSSFNSSSVKSNFASKVNTQLNLLQHSSSNSNFLDASPYDFNKIFMNNFENYDYETD 720 721 EGYAEDDDEEDSDSDNSLPLEIPFKKSKNKCKNRNKELSQRLSLFENRDSNSVDFNTDTN 780 781 LNLNPDSPSVTSSKKKYLDHIILDNRDIVSNHDSSKQKFKIQNILNSTF |
| Interface Residues: | 39, 40, 42, 50, 52, 53, 54, 55, 68, 69, 76, 82 |
| 3D-footprint Homologues: | 1f5e_P, 4umm_E, 1hwt_C, 1pyi_A, 2er8_C, 6o19_A, 7uik_T, 6gys_C, 1d66_B, 3coq_A |
| Binding Motifs: | M1794_1.02 tCsGrrrwww MA0380.1 yYCCGgr MA0380.2 YCCGgr |
| Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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