Transcription Factor
Accessions: | Q02446 (JASPAR 2024) |
Names: | SP4_HUMAN, SPR-1, Transcription factor Sp4 |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | Q02446 |
Length: | 784 |
Pfam Domains: | 647-671 C2H2-type zinc finger 647-671 Zinc finger, C2H2 type 663-690 Zinc-finger double domain 677-701 Zinc finger, C2H2 type 677-701 C2H2-type zinc finger 694-716 Zinc-finger double domain 707-729 Zinc finger, C2H2 type 707-729 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 MSDQKKEEEEEAAAAAAMATEGGKTSEPENNNKKPKTSGSQDSQPSPLALLAATCSKIGT 60 61 PGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQP 120 121 ASSSSSSSSSNNGSASPTKTKSGNSSTPGQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQ 180 181 INPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIP 240 241 LQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVAAGGGTGQVGQPAATADSGTSNGNQL 300 301 VSTPTNTTTSASTMPESPSSSTTCTTTASTSLTSSDTLVSSADTGQYASTSASSSERTIE 360 361 ESQTPAATESEAQSSSQLQPNGMQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAI 420 421 PPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSL 480 481 SNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVAN 540 541 LGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQ 600 601 VHLQQGQQTSDQEVQPGKRLRRVACSCPNCREGEGRGSNEPGKKKQHICHIEGCGKVYGK 660 661 TSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSD 720 721 HLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTN 780 781 MEEF |
Interface Residues: | 634, 636, 637, 638, 639, 643, 659, 660, 661, 662, 663, 665, 666, 668, 669, 672, 689, 690, 691, 692, 693, 695, 696, 697, 700, 717, 718, 719, 720, 721, 722, 723, 724, 725, 728 |
3D-footprint Homologues: | 7eyi_G, 5v3j_F, 2i13_A, 5yel_A, 1tf3_A, 6ml4_A, 7n5w_A, 6jnm_A, 8cuc_F, 2kmk_A, 8ssu_A, 2gli_A, 8gn3_A, 1g2f_F, 6blw_A, 5kkq_D, 1tf6_A, 6u9q_A, 4x9j_A, 1llm_D, 5kl3_A, 1ubd_C, 7ysf_A, 5ei9_F, 8ssq_A, 1mey_C, 5und_A, 5k5i_A, 8h9h_G, 2lt7_A, 7y3m_I, 6e94_A, 6wmi_A, 6a57_A, 2jpa_A, 7w1m_H, 7y3l_A, 3uk3_C, 7txc_E, 2wbs_A, 2drp_D, 1f2i_J, 4m9v_C, 5yj3_D |
Binding Motifs: | MA0685.1 ywrGCCACGCCCmCtyy MA0685.2 gGGGMGGrG |
Publications: | Yokoyama KD, Pollock DD. SP transcription factor paralogs and DNA-binding sites coevolve and adaptively converge in mammals and birds. Genome Biol Evol : (2012;4(11):1102-17.). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.