Transcription Factor

Accessions: 4ond_B (3D-footprint 20210203)
Names: Ancestral SR2 Helix Mutant
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 71
Pfam Domains: 2-69 Zinc finger, C4 type (two domains)
Sequence:
(in bold interface residues)
1 KVCLICGDEASGCHYGVLTCEGCKAFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRL 60
61 RKCLQAGMTLG
Interface Residues: 11, 12, 14, 15, 21, 22, 24, 25, 28, 29, 53
3D-footprint Homologues: 6fbq_A, 6l6q_B, 1a6y_A, 3g9m_B, 1lo1_A, 4oln_B, 2nll_B, 4umm_E, 2han_A, 1kb2_B, 5krb_G, 3cbb_A, 1ynw_B, 1dsz_A, 4iqr_B, 2han_B, 1lat_A, 5l0m_A, 4ond_A, 3dzy_D, 4nqa_H, 2nll_A, 5uan_B, 3e00_A, 2ff0_A, 1hcq_E, 4nqa_I, 1r4i_A, 5va7_A, 5cbz_E, 2c7a_B, 1glu_A, 5e69_A, 4tnt_B, 5emc_A
Binding Motifs: 4ond_AB GGtnAnnnTGaCA
Binding Sites: 4ond_I
4ond_J
Publications: McKeown A.N, Bridgham J.T, Anderson D.W, Murphy M.N, Ortlund E.A, Thornton J.W. Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell 159:58-68 (2014). [Pubmed]
Related annotations: PaperBLAST

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