Transcription Factor
| Accessions: | P63006 (JASPAR 2024) |
| Names: | Homeobox protein Lim-1, LHX1_MOUSE, LIM homeobox protein 1, LIM/homeobox protein Lhx1 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P63006 |
| Length: | 406 |
| Pfam Domains: | 4-59 LIM domain 63-120 LIM domain 181-237 Homeobox domain 203-232 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFG 60 61 TKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLS 120 121 NSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEGGSNENDDQNLGAKR 180 181 RGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQ 240 241 LSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGP 300 301 PSSQAQTPVDLPFVPSSGPSGTPLGGLDHPLPGHHPSSEAQRFTDILAHPPGDSPSPEPS 360 361 LPGPLHSMSAEVFGPSPPFSSLSVNGGASYGNHLSHPPEMNEAAVW |
| Interface Residues: | 180, 181, 182, 183, 184, 222, 223, 225, 226, 229, 230, 233, 234, 236, 237, 247, 322 |
| 3D-footprint Homologues: | 4j19_B, 3a01_E, 2ld5_A, 2lkx_A, 1puf_A, 1ig7_A, 5zfz_A, 1mnm_C, 5zjt_E, 3cmy_A, 6a8r_A, 3d1n_M, 7psx_B, 1fjl_B, 1nk2_P, 1zq3_P, 1k61_B, 5jlw_D, 1b72_A, 4xrs_G, 3l1p_A, 2hdd_A, 6m3d_C, 5flv_I, 3lnq_A, 2r5y_A, 1puf_B, 1jgg_B, 2hos_A, 5hod_A, 3rkq_B, 1au7_A, 4cyc_A, 2h1k_B, 7q3o_C, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1du0_A, 4qtr_D, 6wig_A, 8g87_X, 4xrm_B, 1o4x_A, 6es3_K, 2xkk_C |
| Binding Motifs: | PH0091.1 mgwaTTAATTAAwwahk MA1518.2 rrgtgcTAATTAgcacyy MA1518.3 gcTAATTAgc |
| Binding Sites: | MA1518.2.1 MA1518.2.10 MA1518.2.11 MA1518.2.12 MA1518.2.13 MA1518.2.14 MA1518.2.15 MA1518.2.16 MA1518.2.17 MA1518.2.18 MA1518.2.19 MA1518.2.2 MA1518.2.20 MA1518.2.3 / MA1518.2.5 MA1518.2.4 / MA1518.2.6 MA1518.2.14 / MA1518.2.5 MA1518.2.15 / MA1518.2.6 MA1518.2.20 / MA1518.2.7 MA1518.2.8 MA1518.2.9 MA1518.2.10 MA1518.2.11 MA1518.2.12 MA1518.2.13 MA1518.2.16 MA1518.2.17 MA1518.2.18 MA1518.2.19 MA1518.2.3 MA1518.2.4 MA1518.2.7 MA1518.2.8 MA1518.2.9 MA1518.3.1 MA1518.3.10 MA1518.3.11 MA1518.3.12 MA1518.3.13 MA1518.3.14 MA1518.3.15 MA1518.3.16 MA1518.3.17 MA1518.3.18 MA1518.3.19 MA1518.3.2 MA1518.3.20 MA1518.3.3 MA1518.3.4 MA1518.3.5 MA1518.3.6 MA1518.3.7 MA1518.3.8 MA1518.3.9 |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.