Transcription Factor

Accessions: Q86VK4 (JASPAR 2024)
Names: Another partner for ARF 1, Zinc finger protein 410, Zinc finger protein APA-1, ZN410_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q86VK4
Length: 478
Pfam Domains: 220-243 Zinc finger, C2H2 type
235-261 Zinc-finger double domain
249-273 Zinc finger, C2H2 type
266-292 Zinc-finger double domain
279-303 Zinc finger, C2H2 type
281-303 C2H2-type zinc finger
295-321 Zinc-finger double domain
311-333 C2H2-type zinc finger
311-333 Zinc finger, C2H2 type
325-349 Zinc-finger double domain
339-362 C2H2-type zinc finger
339-361 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDDTT 60
61 NHSNSSKEVPSSAVLRSLRVNVGPDGEETRAQTVQKSPEFLSTSESSSLLQDLQPSDSTS 120
121 FILLNLTRAGLGSSAEHLVFVQDEAEDSGNDFLSSESTDSSIPWFLRVQELAHDSLIAAT 180
181 RAQLAKNAKTSSNGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHL 240
241 KTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHR 300
301 RIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRK 360
361 HHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNLPNTNSILG 420
421 VDDEVLAEGSPRSLSSVPDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERRT
Interface Residues: 231, 232, 234, 235, 238, 261, 262, 263, 264, 265, 267, 268, 270, 271, 274, 291, 292, 293, 294, 295, 296, 297, 298, 299, 301, 302, 321, 322, 323, 324, 325, 326, 327, 328, 329, 350, 351, 352, 353, 354, 355, 356, 357, 360
3D-footprint Homologues: 5v3j_F, 7w1m_H, 1tf6_A, 6wmi_A, 2i13_A, 1ubd_C, 7n5w_A, 6jnm_A, 8cuc_F, 1tf3_A, 7y3l_A, 6ml4_A, 2gli_A, 5kkq_D, 5yel_A, 7txc_E, 5kl3_A, 5ei9_F, 8ssq_A, 8ssu_A, 7eyi_G, 7y3m_I, 6e94_A, 7ysf_A, 6a57_A, 2lt7_A, 2jpa_A, 1g2f_F, 6blw_A, 6u9q_A, 4x9j_A, 5yj3_D, 1mey_C, 5und_A, 2kmk_A, 4m9v_C, 8h9h_G, 3uk3_C, 1llm_D, 2wbs_A, 2drp_D, 1f2i_J, 5k5i_A, 8gn3_A
Binding Motifs: MA0752.1 tmCATCCCATAATAhtc
MA0752.2 mCATCCCATAATAhtc
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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