Transcription Factor

						

			
Accessions: T049232_1.02 (CISBP 1.02)

			
Names: Hic1, T049232_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 893
Pfam Domains:   197-312 BTB/POZ domain
  600-619 C2H2-type zinc finger
  667-689 C2H2-type zinc finger
  667-687 Zinc-finger of C2H2 type
  667-690 C2H2-type zinc finger
  667-689 Zinc finger, C2H2 type
  682-706 Zinc-finger double domain
  695-717 Zinc finger, C2H2 type
  695-717 C2H2-type zinc finger
  695-718 C2H2-type zinc finger
  697-717 Zinc-finger of C2H2 type
  710-734 Zinc-finger double domain
  723-743 C2H2-type zinc finger
  723-745 Zinc finger, C2H2 type
  723-745 C2H2-type zinc finger
  738-761 Zinc-finger double domain
  750-773 C2H2-type zinc finger
  751-773 Zinc finger, C2H2 type
  751-773 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MITRMRHHPWLKSSSFEDRTFPSPPPNWRDITYKYVLGSTQHKTPRFMGLPGPISESPGG   60
  61 HIWKRANLQDLLSSASASLLAQVCARGRSPAAHSPRVAARWRHGRGSVCRFGPLQIRVCG  120
 121 KRGGAETRPGRGEDGPARQTDRGPGGRRAAHCSHVPPWIRRQPGPGLPTCPPGECAGQTM  180
 181 LDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDN  240
 241 LLNLDHDMVSPAVFRLVLDFIYTGRLTDSVEAAAAAAVAPGAEPSLGAVLAAASYLQIPD  300
 301 LVALCKKRLKRHGKYCHLRGGGSGGGGYAPYGRPGRGLRAATPVIQACYSSPAGPPPPPA  360
 361 AEPPSGPDAAVNTHCAELYASGPGPAASLCAPERRCSPLCGLDLSKKSPPGSSVPERPLS  420
 421 ERELPPRPDSPPGAGPAVYKEPSLALPPLPPLPFQKLEEAVPTPDPFRGSGGSPGPEPPG  480
 481 RPDGSSLLYRWMKHEPGLGSYGDELVRDRGSPGERLEERGGDPAASPGGPPLGLVPPPRY  540
 541 PGSLDGPGTGADGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCI  600
 601 PCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVTGAPGGL  660
 661 GELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGL  720
 721 KPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAG  780
 781 AAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHF  840
 841 LHDPKVALESLYPLAKFTAELGLSPDKAAEVLSQGAHLAAGPDSRTIDRFSPT
Interface Residues: 96, 583, 586, 608, 609, 610, 614, 620, 622, 623, 626, 641, 645, 647, 648, 650, 651, 654, 677, 678, 679, 680, 681, 683, 684, 686, 687, 690, 695, 705, 706, 707, 708, 709, 712, 713, 733, 734, 735, 736, 737, 738, 739, 740, 741, 743, 744, 761, 762, 763, 764, 765, 767, 768, 769, 772
3D-footprint Homologues: 3q8p_B, 5v3j_F, 7w1m_H, 1tf3_A, 8cuc_F, 7y3l_A, 2gli_A, 5k5i_A, 8ssq_A, 1tf6_A, 8ssu_A, 6ml4_A, 6blw_A, 5kkq_D, 2drp_D, 5ei9_F, 7eyi_G, 6e94_A, 7ysf_A, 6wmi_A, 2lt7_A, 2i13_A, 2jpa_A, 1ubd_C, 2kmk_A, 6jnm_A, 7n5w_A, 7txc_E, 5kl3_A, 1g2f_F, 5und_A, 4x9j_A, 8gn3_A, 1mey_C, 6u9q_A, 5yel_A, 8h9h_G, 4m9v_C, 7y3m_I, 6a57_A, 3uk3_C, 5yj3_D, 1llm_D, 5k5l_F, 2wbs_A, 1f2i_J
Binding Motifs: M0425_1.02 rgtkGGCAy
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.