Transcription Factor
| Accessions: | P35453 (JASPAR 2024) |
| Names: | Homeobox protein Hox-4I, Homeobox protein Hox-D13, HXD13_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P35453 |
| Length: | 343 |
| Pfam Domains: | 86-175 Hox protein A13 N terminal 277-333 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSRAGSWDMDGLRADGGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAA 60 61 AAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAAAPP 120 121 SAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPA 180 181 NEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNS 240 241 QVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKF 300 301 INKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS |
| Interface Residues: | 276, 277, 278, 279, 280, 318, 319, 321, 322, 325, 326, 329, 330, 333 |
| 3D-footprint Homologues: | 3a01_E, 2h1k_B, 1puf_A, 1ig7_A, 3cmy_A, 6a8r_A, 5zfz_A, 1fjl_B, 2lkx_A, 1jgg_B, 3lnq_A, 1nk2_P, 1zq3_P, 6m3d_C, 7q3o_C, 6es3_K, 2ld5_A, 1b72_A, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 2hdd_A, 2r5y_A, 1puf_B, 5jlw_D, 2hos_A, 4xrs_G, 3rkq_B, 5flv_I, 1le8_A, 1e3o_C, 2xsd_C, 1au7_A, 1mnm_C, 1du0_A, 4qtr_D, 1k61_B, 1o4x_A |
| Binding Motifs: | MA0909.1 symATAAAAm MA0909.2 ssCMATAAAmC |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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