Transcription Factor

Accessions: P20009 (JASPAR 2024)
Names: DLL_DROME, Homeotic protein distal-less, Protein brista
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P20009
Length: 327
Pfam Domains: 125-181 Homeobox domain
Sequence:
(in bold interface residues)
1 MDAPDAPHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGG 60
61 QDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVNGK 120
121 GKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYK 180
181 KMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGGNNGGGSNSGSPSHYLPPGHSPTPS 240
241 STPVSELSPEFPPTGLSPPTQAPWDQKPHWIDHKPPPQMTPQPPHPAATLHPQTHHHNPP 300
301 PQMGGYVPQYWYQPETNPSLVTVWPAV
Interface Residues: 125, 126, 127, 128, 166, 167, 169, 170, 173, 174, 177, 178, 181
3D-footprint Homologues: 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1fjl_B, 5zfz_A, 1ig7_A, 5zjt_E, 2h1k_B, 1nk2_P, 1zq3_P, 6m3d_C, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 1jgg_B, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 3a01_E, 7psx_B, 5hod_A, 3lnq_A, 1e3o_C, 1au7_A, 7xrc_C, 2xsd_C, 1le8_A, 4xrm_B, 1mnm_C, 1k61_B, 3l1p_A, 1o4x_A, 8g87_X, 4qtr_D, 1le8_B, 1du0_A
Binding Motifs: MA0187.1 TAATTry
Binding Sites: MA0187.1.1
MA0187.1.10
MA0187.1.11
MA0187.1.12
MA0187.1.13
MA0187.1.14
MA0187.1.15
MA0187.1.16
MA0187.1.17
MA0187.1.18
MA0187.1.19
MA0187.1.2
MA0187.1.20
MA0187.1.3
MA0187.1.4
MA0187.1.5
MA0187.1.6
MA0187.1.7
MA0187.1.8
MA0187.1.9
Publications: Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.