Transcription Factor
| Accessions: | P31368 (JASPAR 2024) |
| Names: | dOCT1, dPOU-19, PDM-1, PDM1_DROME, POU domain protein 1, Protein nubbin, Protein twain |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 601 |
| Pfam Domains: | 422-495 Pou domain - N-terminal to homeobox domain 524-580 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MVMSELRWHTASPEDNKNSLKRDLLKSTPTSAREAAVHIMQNRYISRLSRSPSPLQSNAS 60 61 DCDDNNSSVGTSSDRCRSPLSPALSLSHQQAKRQLMSLQPHPAHHHHNPHHLNHLNHHQY 120 121 KQEEDYDDANGGALNLTSDNSRHSTQSPSNSVKSATASPVPVISVPSPVPPMISPVLAPS 180 181 GCGSTTPNSMAAAAAAAAAVASTMGSGISPLLALPGMSSPQAQLAAAGLGMNNPLLTGSL 240 241 SPQDFAQFHQLLQQRQVALTQQFNSYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQLQ 300 301 ALSQASQQLQALQKQQQRQVDEPLQLNHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHH 360 361 HHHHPLQITPPSSAASLKLSGMLTPSTPTSGTQMSQGTTTPQPKTVASAAAARAAGEPSP 420 421 EETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNM 480 481 CKLKPLLQKWLDDADRTIQATGGVFDPAALQATVSTPEIIGRRRKKRTSIETTIRGALEK 540 541 AFLANQKPTSEEITQLADRLSMEKEVVRVWFCNRRQKEKRINPSLDSPTGADDDESSYMM 600 601 H |
| Interface Residues: | 447, 463, 464, 465, 466, 468, 469, 475, 479, 524, 525, 526, 527, 565, 566, 568, 569, 572, 573, 576, 577, 580 |
| 3D-footprint Homologues: | 3d1n_M, 3l1p_A, 7u0g_M, 1o4x_A, 8g87_X, 7xrc_C, 1e3o_C, 7xzx_N, 1au7_A, 2xsd_C, 7xzz_N, 3cmy_A, 2h1k_B, 5zfz_A, 1puf_A, 5zjt_E, 1puf_B, 1fjl_B, 6a8r_A, 1ig7_A, 1jgg_B, 1nk2_P, 1zq3_P, 3lnq_A, 2lkx_A, 2ld5_A, 4xrs_G, 3rkq_B, 2r5y_A, 7psx_B, 2hdd_A, 5hod_A, 1b72_A, 3a01_E, 5jlw_D, 1le8_A, 7q3o_C, 1du0_A, 6es3_K, 5flv_I, 4cyc_A, 4qtr_D |
| Binding Motifs: | MA0197.1 kwTAATkA MA0197.2 TATGyAAATkag MA0197.3 TATGyAAATka |
| Binding Sites: | MA0197.1.3 MA0197.1.1 MA0197.1.10 MA0197.1.11 MA0197.1.12 MA0197.1.13 MA0197.1.14 MA0197.1.15 MA0197.1.16 MA0197.1.17 MA0197.1.18 MA0197.1.19 MA0197.1.2 MA0197.1.20 MA0197.1.4 MA0197.1.5 MA0197.1.6 MA0197.1.7 MA0197.1.8 MA0197.1.9 MA0197.2.1 MA0197.2.10 MA0197.2.11 MA0197.2.12 MA0197.2.13 MA0197.2.14 MA0197.2.15 MA0197.2.16 MA0197.2.17 MA0197.2.18 MA0197.2.19 MA0197.2.2 MA0197.2.20 MA0197.2.3 MA0197.2.4 MA0197.2.5 MA0197.2.6 MA0197.2.7 MA0197.2.8 MA0197.2.9 MA0197.3.1 / MA0197.3.3 MA0197.3.10 MA0197.3.11 MA0197.3.12 MA0197.3.13 MA0197.3.14 MA0197.3.15 MA0197.3.16 MA0197.3.17 MA0197.3.18 / MA0197.3.4 MA0197.3.19 MA0197.3.2 / MA0197.3.7 MA0197.3.20 MA0197.3.5 MA0197.3.6 MA0197.3.8 MA0197.3.9 |
| Publications: | Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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