Transcription Factor
| Accessions: | Q14B70 (JASPAR 2024) |
| Names: | HDX_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q14B70 |
| Length: | 692 |
| Pfam Domains: | 440-497 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MNLRSVFTVEQQRILQRYYENGMTNQSKNCFQLILQCAQETKLDFSVVRTWVGNKRRKMS 60 61 SKSCESGAAGTVSGTSLAAPDITVRNVVNIARPSSQQSSWTSANNDVIVTGIYSPVSSSS 120 121 KQGTTKHTNTQITEAHKIPIQKAANKNDTELQLHIPVQRQVAHCKNASVLLGEKTIILSR 180 181 QTSVLNAGNSVYNHTKKSYGSSPVQASEMTVPQKPSVCQRPCKIEPVGIQRSYKPEHAGL 240 241 ASHNLCGQKPTIRDPCCRTQNLEIREVFSLAVSDYPQRILGGNSTQKPASAEGTCLSIAM 300 301 ETGDAEDEYAREEELASMGAQITSYSRFYESGNSLRAENQSTNLPGPGRNLPNSQMVNIR 360 361 DLSDNVLYQTRDYHLTPRTSLHTASSTMYSNTNPSRSNFSPHFVSSNQLRLSQNQNNYQI 420 421 SGNLSVPWITGCSRKRALQDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVAIELNV 480 481 DCEIVRTWIGNRRRKYRLMGIEVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDND 540 541 RNDEVSICLSEASSQEESNELIPNETRAHKDEEHQAVSADNVKIEIIDDEESDMISNSEV 600 601 EQENSLLDYKNEEVRFIENELEIQKQKYFKLQSFVRNLILAMKADDKDQQQALLSDLPPE 660 661 LEEMDCSHASPDPDDTSLSVSSLSEKNASDSL |
| Interface Residues: | 4, 49, 50, 53, 54, 57, 58, 436, 441, 486, 487, 490, 491, 494, 495 |
| 3D-footprint Homologues: | 5hod_A, 1au7_A, 1k61_B, 1mnm_C, 8g87_X, 3d1n_M, 1e3o_C, 2xsd_C, 7xrc_C, 2lkx_A, 1o4x_A, 3l1p_A |
| Binding Motifs: | PH0037.1 wrkkmGAAATCAtcbha |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.