Transcription Factor
| Accessions: | Stat92E (DrosophilaTF 1.1), Q24151 (JASPAR 2024) |
| Names: | d-STAT, Protein marelle, Signal transducer and transcription activator, STAT_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 761 |
| Pfam Domains: | 2-118 STAT protein, protein interaction domain 141-340 STAT protein, all-alpha domain 342-588 STAT protein, DNA binding domain 599-642 SH2 domain |
| Sequence: (in bold interface residues) | 1 MSLWKRISSHVDCEQRMAAYYEEKGMLELRLCLAPWIEDRIMSEQITPNTTDQLERVALK 60 61 FNEDLQQKLLSTRTASDQALKFRVVELCALIQRISAVELYTHLRSGLQKELQLVTEKSVA 120 121 ATAGQSMPLNPYNMNNTPMVTGYMVDPSDLLAVSNSCNPPVVQGIGPIHNVQNTGIASPA 180 181 LGMVTPKVELYEVQHQIMQSLNEFGNCANALKLLAQNYSYMLNSTSSPNAEAAYRSLIDE 240 241 KAAIVLTMRRSFMYYESLHEMVIHELKNWRHQQAQAGNGAPFNEGSLDDIQRCFEMLESF 300 301 IAHMLAAVKELMRVRLVTEEPELTHLLEQVQNAQKNLVCSAFIVDKQPPQVMKTNTRFAA 360 361 SVRWLIGSQLGIHNNPPTVECIIMSEIQSQRFVTRNTQMDNSSLSGQSSGEIQNASSTME 420 421 YQQNNHVFSASFRNMQLKKIKRAEKKGTESVMDEKFALFFYTTTTVNDFQIRVWTLSLPV 480 481 VVIVHGNQEPQSWATITWDNAFAEIVRDPFMITDRVTWAQLSVALNIKFGSCTGRSLTID 540 541 NLDFLYEKLQREERSEYITWNQFCKEPMPDRSFTFWEWFFAIMKLTKDHMLGMWKAGCIM 600 601 GFINKTKAQTDLLRSVYGIGTFLLRFSDSELGGVTIAYVNENGLVTMLAPWTARDFQVLN 660 661 LADRIRDLDVLCWLHPSDRNASPVKRDVAFGEFYSKRQEPEPLVLDPVTGYVKSTLHVHV 720 721 CRNGENGSTSGTPHHAQESMQLGNGDFGMADFDTITNFENF |
| Interface Residues: | 353, 449, 484, 485, 486, 487, 488 |
| 3D-footprint Homologues: | 1bf5_A, 1bg1_A, 4y5w_B |
| Binding Motifs: | Stat92E dvakwTTTCCsgGAAAyrsyd MA0532.1 cgsAwTTCyrrGAAw MA0532.2 AwTTCyrrGAAw |
| Binding Sites: | Stat92E_Yan, et al. 1 Stat92E_Yan, et al. 10 Stat92E_Yan, et al. 11 Stat92E_Yan, et al. 12 Stat92E_Yan, et al. 13 Stat92E_Yan, et al. 14 Stat92E_Yan, et al. 15 Stat92E_Yan, et al. 16 Stat92E_Yan, et al. 17 Stat92E_Yan, et al. 18 Stat92E_Yan, et al. 19 Stat92E_Yan, et al. 2 Stat92E_Yan, et al. 20 Stat92E_Yan, et al. 21 Stat92E_Yan, et al. 22 Stat92E_Yan, et al. 23 Stat92E_Yan, et al. 24 Stat92E_Yan, et al. 25 Stat92E_Yan, et al. 26 Stat92E_Yan, et al. 27 Stat92E_Yan, et al. 28 Stat92E_Yan, et al. 29 Stat92E_Yan, et al. 3 Stat92E_Yan, et al. 30 Stat92E_Yan, et al. 4 Stat92E_Yan, et al. 5 Stat92E_Yan, et al. 6 Stat92E_Yan, et al. 7 Stat92E_Yan, et al. 8 Stat92E_Yan, et al. 9 MA0532.1.1 MA0532.1.10 MA0532.1.11 MA0532.1.12 MA0532.1.13 MA0532.1.14 MA0532.1.15 MA0532.1.16 MA0532.1.17 MA0532.1.18 MA0532.1.19 MA0532.1.2 MA0532.1.20 MA0532.1.3 MA0532.1.4 MA0532.1.5 MA0532.1.6 MA0532.1.7 MA0532.1.8 MA0532.1.9 MA0532.2.1 MA0532.2.10 MA0532.2.11 MA0532.2.12 MA0532.2.13 MA0532.2.14 MA0532.2.15 MA0532.2.16 MA0532.2.17 MA0532.2.18 MA0532.2.19 MA0532.2.2 MA0532.2.20 MA0532.2.3 MA0532.2.4 MA0532.2.5 MA0532.2.6 MA0532.2.7 MA0532.2.8 MA0532.2.9 |
| Publications: | Yan R., Small S., Desplan C., Dearolf C. R., Darnell jr J. E. Identification of a STAT gene that functions in Drosophila development. Cell 84:421-430 (1996). [Pubmed] |
| Related annotations: | PaperBLAST |
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