Transcription Factor
| Accessions: | ZNF692 (humanC2H2ZF-ChIP Feb2015), Q9BU19 (JASPAR 2024) |
| Names: | ENSG00000171163, Q9BU19, ZNF692, AICAR responsive element binding protein, Zinc finger protein 692, ZN692_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | humanC2H2ZF-ChIP Feb2015 1, JASPAR 2024 2 1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | TF family: C2H2 experiment: ChIP-seq/MEME/B1H-RC |
| Length: | 519 |
| Pfam Domains: | 329-350 C2H2-type zinc finger 359-383 Zinc finger, C2H2 type 359-383 C2H2-type zinc finger 375-400 Zinc-finger double domain 389-411 Zinc finger, C2H2 type 389-411 C2H2-type zinc finger 403-426 Zinc-finger double domain 418-439 Zinc finger, C2H2 type 418-439 C2H2-type zinc finger 431-458 Zinc-finger double domain 448-471 Zinc finger, C2H2 type 448-471 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MASSPAVDVSCRRREKRRQLDARRSKCRIRLGGHMEQWCLLKERLGFSLHSQLAKFLLDR 60 61 YTSSGCVLCAGPEPLPPKGLQYLVLLSHAHSRECSLVPGLRGPGGQDGGLVWECSAGHTF 120 121 SWGPSLSPTPSEAPKPASLPHTTRRSWCSEATSGQELADLESEHDERTQEARLPRRVGPP 180 181 PETFPPPGEEEGEEEEDNDEDEEEMLSDASLWTYSSSPDDSEPDAPRLLPSPVTCTPKEG 240 241 ETPPAPAALSSPLAVPALSASSLSSRAPPPAEVRVQPQLSRTPQAAQQTEALASTGSQAQ 300 301 SAPTPAWDEDTAQIGPKRIRKAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQHIHQKSFS 360 361 CPEPACGKSFNFKKHLKEHMKLHSDTRDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCE 420 421 ICGFTCRQKASLNWHQRKHAETVAALRFPCEFCGKRFEKPDSVAAHRSKSHPALLLAPQE 480 481 SPSGPLEPCPSISAPGPLGSSEGSRPSASPQAPTLLPQQ |
| Interface Residues: | 340, 341, 342, 343, 344, 347, 351, 359, 371, 372, 373, 374, 375, 377, 378, 380, 381, 382, 384, 399, 400, 401, 402, 403, 405, 406, 407, 409, 427, 428, 429, 430, 431, 432, 433, 434, 435, 437, 438, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468 |
| 3D-footprint Homologues: | 1tf3_A, 8ssq_A, 5kkq_D, 8ssu_A, 5yel_A, 6wmi_A, 5ei9_F, 7w1m_H, 1tf6_A, 2i13_A, 2kmk_A, 7n5w_A, 6jnm_A, 1f2i_J, 2gli_A, 1g2f_F, 6blw_A, 4x9j_A, 8gn3_A, 5kl3_A, 7ysf_A, 1mey_C, 7eyi_G, 8h9h_G, 2lt7_A, 6e94_A, 6a57_A, 2jpa_A, 1ubd_C, 5und_A, 8cuc_F, 7y3l_A, 3uk3_C, 5k5i_A, 6ml4_A, 5v3j_F, 6u9q_A, 1llm_D, 7txc_E, 2wbs_A, 4m9v_C, 8gh6_A, 7y3m_I, 2drp_D, 5yj3_D |
| Binding Motifs: | ZNF692_ChIP kGTGGGcCCCrsc MA1986.1 kgGGCCCAss MA1986.2 gGGCCCAs |
| Binding Sites: | MA1986.1.1 MA1986.1.10 / MA1986.1.13 MA1986.1.11 / MA1986.1.14 MA1986.1.12 / MA1986.1.15 MA1986.1.13 / MA1986.1.17 MA1986.1.14 / MA1986.1.19 MA1986.1.15 / MA1986.1.20 MA1986.1.16 MA1986.1.17 MA1986.1.18 MA1986.1.19 MA1986.1.2 / MA1986.1.6 / MA1986.1.7 MA1986.1.10 / MA1986.1.20 / MA1986.1.9 MA1986.1.3 / MA1986.1.7 / MA1986.1.8 MA1986.1.4 MA1986.1.5 MA1986.1.8 / MA1986.1.9 MA1986.1.11 MA1986.1.12 MA1986.1.16 MA1986.1.18 MA1986.1.6 MA1986.2.1 / MA1986.2.2 / MA1986.2.3 / MA1986.2.6 / MA1986.2.7 MA1986.2.10 MA1986.2.11 / MA1986.2.17 MA1986.2.12 / MA1986.2.14 / MA1986.2.20 / MA1986.2.5 / MA1986.2.9 MA1986.2.13 / MA1986.2.18 / MA1986.2.19 / MA1986.2.8 MA1986.2.15 MA1986.2.16 MA1986.2.4 |
| Publications: | Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.