Transcription Factor

						

			
Accessions: byn (DrosophilaTF 1.1)

			
Names: BYN_DROME, Protein brachyenteron, T-related protein, Trp
Organisms: Drosophila melanogaster
Libraries: DrosophilaTF 1.1 1
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]
Uniprot: P55965
Length: 697
Pfam Domains:    89-264 T-box
Sequence: 
(in bold interface residues)		   1 MTTSHILSAVDPTTGLSGNVSGGGGGGGAGGGAGSGSPQHVTHNGHGHGHGLGGVAAVSG   60
  61 GGASVSGNGGHRVVGGAGSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVV  120
 121 KISASGLDPAAMYTVLLEFVQIDSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFGAH  180
 181 WMKEPISFAKVKLTNKTNGNGQIMLNSLHKYEPRVHLVRVGSEQRHVVTYPFPETQFIAV  240
 241 TAYQNEEVTSLKIKYNPFAKAFLDAKERPDTLYPHDTHYGWLIPPPTHYTAAAAAVAAPP  300
 301 PLSIAQSHGLVASCPSVSSAESVGPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGS  360
 361 GSNGSAGNASSTSPQPPSAPQTPTSLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYA  420
 421 QSGFMSVDASPTASVFSYPSSWQSNGNYWNATSVPGPMPMNVCSGRNISSHNSPSPTNGS  480
 481 PSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTGVGVGGGAGTTGSPQAAYGAAAHQVYHP  540
 541 TPTSPTHQLYTNAVLNAPSALSYSASGWHNGSGAEYGLYQNAAAAYYQPEYIPLEIGYAT  600
 601 HPLEPVDVSKTLDDPQAAMYKPSDEQGSVITLECASSSLKSSHDIKIESSSLEHAGERGT  660
 661 VGGGAAVVSVPTAVVNGAPAVAADTWTPLTPPQSTLQ
Interface Residues: 114, 241, 242, 258, 261, 262
3D-footprint Homologues: 5flv_I, 1xbr_B, 6f59_B, 2x6v_A, 4a04_B, 1h6f_B
Binding Motifs: byn rwwnTnrCACyT
			
Publications: Kusch Thomas, Storck Tobias, Walldorf Uwe, Reuter Rolf. Brachyury proteins regulate target genes through modular binding sites in a cooperative fashion.. Genes Dev. 16:518-529 (2002). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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