Transcription Factor

						

			
Accessions: 1a02_F (3D-footprint 20231221)

			
Names: AP-1 FRAGMENT FOS, Cellular oncogene fos, FOS_HUMAN, G0/G1 switch regulatory protein 7, Proto-oncogene c-Fos
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P01100
Length: 53
Pfam Domains:      1-52 bZIP transcription factor
     2-50 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 RRIRRERNKMAAAKSRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEK
Interface Residues: 4, 5, 8, 9, 11, 12, 15, 16
3D-footprint Homologues: 7x5e_F, 2wt7_A, 1nwq_C, 6mg1_B, 5t01_B, 2dgc_A, 5vpe_C, 4eot_A
Binding Motifs: 1a02_F ATGAA
1a02_FJN GGAananwTGnyTCA
Binding Sites: 1a02_A
1a02_B
			
Publications: Chen L., Glover J. N. M., Hogan P. G., Rao A., Harrison S. C. Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.. Nature 392:42-48 (1998). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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