Transcription Factor
| Accessions: | Q9BZM3 (JASPAR 2024) |
| Names: | Genetic-screened homeobox 2, GS homeobox 2, GSX2_HUMAN, Homeobox protein GSH-2 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9BZM3 |
| Length: | 304 |
| Pfam Domains: | 203-259 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRKSGAFCV 60 61 CPLCVTSHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKGQFSSAPGDAQFCP 120 121 RVNHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNV 180 181 ADPRRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLN 240 241 LSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKE 300 301 ISPL |
| Interface Residues: | 185, 191, 195, 203, 204, 205, 206, 207, 244, 245, 247, 248, 251, 252, 255, 256, 259 |
| 3D-footprint Homologues: | 1e3o_C, 1fjl_B, 6a8r_A, 2h1k_B, 1puf_A, 1ig7_A, 3cmy_A, 5zfz_A, 1jgg_B, 3d1n_M, 1zq3_P, 3lnq_A, 2lkx_A, 1nk2_P, 2ld5_A, 7q3o_C, 6es3_K, 1puf_B, 6m3d_C, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 3a01_E, 1b72_A, 5jlw_D, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 2xsd_C, 1au7_A, 1le8_A, 7xrc_C, 8g87_X, 1k61_B, 3l1p_A, 1o4x_A, 4qtr_D, 1mnm_C, 1du0_A |
| Binding Motifs: | MA0893.1 mcymATTAaa MA0893.2 symATTAr MA0893.3 symATTA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.