Transcription Factor
| Accessions: | T093317_1.02 (CISBP 1.02), P52954 (JASPAR 2024) |
| Names: | LBX1, T093317_1.02;, Ladybird homeobox protein homolog 1, LBX1_HUMAN, Transcription factor LBX1 |
| Organisms: | Homo sapiens |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Homeodomain |
| Length: | 281 |
| Pfam Domains: | 126-182 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MTSKEDGKAAPGEERRRSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHLL 60 61 AAADKHAQGGLPLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQ 120 121 TPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKL 180 181 KRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPG 240 241 APKAPGAGALQLSPASPLTDQPASSQDCSEDEEDEEIDVDD |
| Interface Residues: | 124, 125, 126, 127, 128, 129, 167, 168, 170, 171, 174, 175, 178, 179, 182 |
| 3D-footprint Homologues: | 6fqp_B, 5zfz_A, 4j19_B, 1fjl_B, 3cmy_A, 2h1k_B, 1puf_A, 1ig7_A, 6a8r_A, 3d1n_M, 1jgg_B, 1nk2_P, 1zq3_P, 3lnq_A, 2lkx_A, 1puf_B, 6es3_K, 2ld5_A, 7q3o_C, 5jlw_D, 4cyc_A, 2r5y_A, 4xrs_G, 3l1p_A, 2hos_A, 7psx_B, 3a01_E, 5flv_I, 5zjt_E, 1b72_A, 5hod_A, 3rkq_B, 2hdd_A, 6m3d_C, 1e3o_C, 1le8_A, 1du0_A, 1k61_B, 1o4x_A, 4qtr_D, 6fqq_E, 8g87_X, 4xrm_B, 1mnm_C |
| Binding Motifs: | M0894_1.02 tTAAYTRG MA0618.1 tTAAYTRG MA0618.2 TAAYTRG |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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