Transcription Factor

Accessions: slbo (DrosophilaTF 1.1), Q02637 (JASPAR 2024)
Names: C/EBP, CCAAT/enhancer-binding protein, CEBP_DROME, Slow border cell protein
Organisms: Drosophila melanogaster
Libraries: DrosophilaTF 1.1 1, JASPAR 2024 2
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q02637
Length: 449
Pfam Domains: 363-415 Basic region leucine zipper
366-421 bZIP transcription factor
Sequence:
(in bold interface residues)
1 MLNMESPQMYADAVQTLAQLDLKKEPPLQQATIGQITLTAMSTAQQQQQQQQQQQQQQQQ 60
61 QQQQQQQQPQQQTTDANNNTSQDAALLVKQHAMHQMQQVAALGSNNNLLQKQMLQQYSTQ 120
121 TDLDELTTQEITLDLQHLIDDQFRDTETLGIFSDMVTSPGGLSATLPPSGMVSAAAKVLQ 180
181 QQTLRNQHGYGGRGGGGGAGGALAYMPQPVHATYNNSSDENSSVGSDSSTIKEEPIDPEY 240
241 RRHLQEAASQQAAFMGNGAGLYNGYGSGANGLTGGGNPLNGGNTTPSSNGSNGSTGSSNG 300
301 SQFTNLTTANVLAHHNLPHLAAAAGAHNLLKQHSKLHAQQQHQQHQQQQQHRKHSNKHVD 360
361 KGTDEYRRRRERNNIAVRKSREKAKVRSREVEERVKSLLKEKDALIRQLGEMTNELQLHK 420
421 QIYMQLMNHANPEVSRVCRSFLNTNEHSL
Interface Residues: 369, 370, 373, 374, 376, 377, 380, 381
3D-footprint Homologues: 7x5e_F, 2wt7_A, 1nwq_C, 6mg1_B, 5t01_B
Binding Motifs: MA0244.1 ATKrCamA
slbo TTnnrCAATm
Binding Sites: MA0244.1.1
MA0244.1.10
MA0244.1.11
MA0244.1.12
MA0244.1.2
MA0244.1.3
MA0244.1.4
MA0244.1.5
MA0244.1.6
MA0244.1.7
MA0244.1.8
MA0244.1.9
Publications: Murphy A. M., Lee T., Andrews C. M., Shilo B. Z., Montell D. J. The breathless FGF receptor homolog, a downstream target of Drosophila C/EBP in the developmental control of cell migration.. Development 121:2255-2263 (1995). [Pubmed]

Bergman C.M, Carlson J.W, Celniker S.E. Drosophila DNase I footprint database: a systematic genome annotation of transcription factor binding sites in the fruitfly, Drosophila melanogaster. Bioinformatics (Oxford, England) 21:1747-9 (2005). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.