Transcription Factor
Accessions: | P32182 (JASPAR 2024) |
Names: | Forkhead box protein A2, FOXA2_RAT, Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B |
Organisms: | Rattus norvegicus |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Length: | 458 |
Pfam Domains: | 17-158 Forkhead N-terminal region 159-253 Fork head domain 373-447 HNF3 C-terminal domain |
Sequence: (in bold interface residues) | 1 MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNASLGMNGMNTYMSMSAAAMGSGSGNMSA 60 61 GSMNMSSYVGAGMSPSLAGMSPGAGAMAGMSGSAGAAGVAGMGPHLSPSLSPLGGQAAGA 120 121 MGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKML 180 181 TLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDFLKVPRAPDKPGKGSFWTLHPDSGN 240 241 MFENGCYLRRQKRFKCENELALKEAAGAGSGGGKKTAPGTQASQVQLGEAAGSASETPAG 300 301 TESPHSSASPCQEHKRGGLSELKGTPASALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPP 360 361 EAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKTYEQVMHYPGGYGSPMP 420 421 GSLAMGPVTNKAGLDASPLAADTSYYQGVYSRPIMNSS |
Interface Residues: | 149, 151, 153, 154, 156, 202, 204, 205, 206, 208, 209, 210, 212, 213, 221, 228, 253 |
3D-footprint Homologues: | 7yz7_A, 7yzb_A, 7vox_H, 2hdc_A, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 6el8_A, 7tdx_A, 3l2c_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 3qrf_G |
Binding Motifs: | MA0047.1 mawTrTTkryTY |
Binding Sites: | MA0047.1.4 MA0047.1.10 MA0047.1.5 MA0047.1.7 MA0047.1.1 MA0047.1.11 MA0047.1.12 MA0047.1.13 MA0047.1.14 MA0047.1.15 MA0047.1.16 MA0047.1.17 MA0047.1.2 MA0047.1.3 MA0047.1.6 MA0047.1.8 MA0047.1.9 |
Publications: | Overdier D. G., Porcella A., Costa R. H. The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino acid residues adjacent to the recognition helix. Mol. Cell. Biol. 14:2755-2766 (1994). [Pubmed] |
Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.